C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Transcript Info
Description: nemo like kinase
Transcript Accession Transcript Name Contained in Gene Tax ID Strand Position Biotype
ENSMUST00000142739 Nlk-001 ENSMUSG00000017376 10090 - 11:78567168-78697373 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENSMUST00000142739
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENSMUST00000142739 3.650±1.80 21.527±2.52 6.793±0.90 12.989±3.93 4.495±2.87 2.713±1.27 2.301±0.39 4.085±1.41 2.442±0.83 7.163±1.29 2.103±0.42 7.572±4.05 5.767±3.47 2.952±1.52

Conserved Regions

Gene is not located within a conserved region.

Gene Ontology

GO IDEvidence TypeGO Description
GO:0000165 IEA MAPK cascade
GO:0000287 IDA magnesium ion binding
GO:0004672 IDA protein kinase activity
GO:0004674 IDA protein serine/threonine kinase activity
GO:0004707 IDA MAP kinase activity
GO:0005515 IPI protein binding
GO:0005524 IDA ATP binding
GO:0005634 IDA nucleus
GO:0005737 IEA cytoplasm
GO:0006351 IEA transcription, DNA-templated
GO:0006355 IMP regulation of transcription, DNA-templated
GO:0006468 IDA protein phosphorylation
GO:0007179 ISS transforming growth factor beta receptor signaling pathway
GO:0008134 ISS transcription factor binding
GO:0016055 IEA Wnt signaling pathway
GO:0018107 IDA peptidyl-threonine phosphorylation
GO:0030178 IMP negative regulation of Wnt signaling pathway
GO:0031625 ISS ubiquitin protein ligase binding
GO:0033136 IDA serine phosphorylation of STAT3 protein
GO:0035556 IDA intracellular signal transduction
GO:0042169 IPI SH2 domain binding
GO:0046777 IDA protein autophosphorylation

Homologs

ENSEMBL Accession Gene Name Biotype Species E-Value Bit Score
ENST00000407008 NLK-001 protein_coding Homo_sapiens 0 5227
ENST00000496808 NLK-002 nonsense_mediated_decay Homo_sapiens 0 2289
ENST00000582037 NLK-004 protein_coding Homo_sapiens 0 769
ENST00000583517 NLK-003 processed_transcript Homo_sapiens 0 387
ENST00000584188 NLK-005 processed_transcript Homo_sapiens 0 490
ENST00000584878 NLK-006 retained_intron Homo_sapiens 0 948

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