C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: insulin-like growth factor binding protein 4
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSMUSG00000017493 Igfbp4 10090 + 11:99041244-99054392 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENSMUST00000017637 Igfbp4-001 99041244-99054392 protein_coding
  ENSMUST00000123946 Igfbp4-003 99044766-99051815 processed_transcript
  ENSMUST00000130530 Igfbp4-004 99043597-99051920 processed_transcript
  ENSMUST00000140772 Igfbp4-002 99047311-99051812 protein_coding
  ENSMUST00000177092 Igfbp4-005 99041760-99051701 protein_coding
  ENSMUST00000177105 Igfbp4-006 99042186-99048360 processed_transcript

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENSMUST00000017637ENSMUST00000130530ENSMUST00000140772ENSMUST00000177092
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENSMUST00000017637 160.674±49.56 26.242±8.39 65.402±0.31 11.203±4.78 80.045±36.43 23.390±3.68 19.406±2.55 150.387±32.61 240.638±223.33 58.379±5.84 3.172±3.22 79.902±75.22 20.759±20.42 1.042±0.58
ENSMUST00000130530 338.460±84.60 N/A 69.399±12.15 25.858±1.16 138.819±16.58 70.946±6.24 41.679±4.56 195.574±18.06 277.786±272.22 93.041±28.90 8.155±3.19 118.187±23.89 38.449±14.60 3.268±0.25
ENSMUST00000140772 N/A N/A N/A N/A 89.599±1.49 65.543±0.00 N/A 200.662±21.98 N/A 64.399±0.56 N/A N/A N/A N/A
ENSMUST00000177092 N/A N/A N/A 32.540±0.00 N/A N/A N/A N/A N/A N/A N/A 170.235±0.00 29.957±1.20 N/A

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_00098Y CIL_00098Y_0002 VISTA 11:98447152-99051430
CIL_0005R1 CIL_0005R1_0002 CGP 11:98992943-99054392
CIL_0005R3 CIL_0005R3_0002 CGP 11:99041244-99089306

Gene Ontology
GO IDEvidence TypeGO Description
GO:0001558 IGI regulation of cell growth
GO:0005520 IPI insulin-like growth factor binding
GO:0005615 IDA extracellular space
GO:0006954 IEA inflammatory response
GO:0010906 IGI regulation of glucose metabolic process
GO:0040008 IGI regulation of growth
GO:0043410 IGI positive regulation of MAPK cascade
GO:0043568 IGI positive regulation of insulin-like growth factor receptor signaling pathway
GO:0044342 IGI type B pancreatic cell proliferation

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSG00000141753 IGFBP4 insulin-like growth factor binding protein 4 protein_coding Homo_sapiens

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