C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: adenosine deaminase
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSMUSG00000017697 Ada 10090 - 2:163726584-163750239 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENSMUST00000017841 Ada-001 163726584-163750239 protein_coding
  ENSMUST00000156939 Ada-002 163730015-163730866 processed_transcript

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENSMUST00000017841ENSMUST00000156939
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENSMUST00000017841 1.716±0.59 0.440±0.11 3.996±0.20 0.787±0.37 1.061±0.38 1.986±0.32 0.257±0.13 0.739±0.33 1.559±1.13 23.371±23.14 0.164±0.08 6.861±2.16 167.283±44.46 1.465±0.54
ENSMUST00000156939 N/A N/A N/A N/A N/A N/A 0.199±0.00 N/A N/A N/A N/A N/A N/A N/A

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0007R9 CIL_0007R9_0002 VISTA 2:163385776-163987192
CIL_0006IR CIL_0006IR_0003 CGP 2:163658386-163750239
CIL_0006IS CIL_0006IS_0003 CGP 2:163726584-163833146

Gene Ontology
GO IDEvidence TypeGO Description
GO:0001666 IEA response to hypoxia
GO:0001701 IMP in utero embryonic development
GO:0001821 IEA histamine secretion
GO:0001829 IMP trophectodermal cell differentiation
GO:0001883 IEA purine nucleoside binding
GO:0001889 IMP liver development
GO:0001890 IMP placenta development
GO:0002314 IMP germinal center B cell differentiation
GO:0002636 IMP positive regulation of germinal center formation
GO:0002686 IGI negative regulation of leukocyte migration
GO:0002906 IMP negative regulation of mature B cell apoptotic process
GO:0004000 IMP adenosine deaminase activity
GO:0005515 IEA protein binding
GO:0005615 IEA extracellular space
GO:0005737 IDA cytoplasm
GO:0005764 IEA lysosome
GO:0005829 IBA cytosol
GO:0005886 IEA plasma membrane
GO:0006154 IMP adenosine catabolic process
GO:0006157 IMP deoxyadenosine catabolic process
GO:0007155 IEA cell adhesion
GO:0007568 IEA aging
GO:0008270 IDA zinc ion binding
GO:0009168 IEA purine ribonucleoside monophosphate biosynthetic process
GO:0009897 IBA external side of plasma membrane
GO:0009986 IEA cell surface
GO:0010460 IMP positive regulation of heart rate
GO:0016020 IEA membrane
GO:0030054 IEA cell junction
GO:0030324 IMP lung development
GO:0030890 IMP positive regulation of B cell proliferation
GO:0031410 IEA cytoplasmic vesicle
GO:0032261 IEA purine nucleotide salvage
GO:0032839 IEA dendrite cytoplasm
GO:0033089 IMP positive regulation of T cell differentiation in thymus
GO:0033197 IEA response to vitamin E
GO:0033632 IEA regulation of cell-cell adhesion mediated by integrin
GO:0042110 IEA T cell activation
GO:0042323 IEA negative regulation of circadian sleep/wake cycle, non-REM sleep
GO:0042493 IEA response to drug
GO:0042542 IEA response to hydrogen peroxide
GO:0043025 IEA neuronal cell body
GO:0043066 IMP negative regulation of apoptotic process
GO:0043103 IBA hypoxanthine salvage
GO:0043278 IEA response to morphine
GO:0045187 IEA regulation of circadian sleep/wake cycle, sleep
GO:0045580 IMP regulation of T cell differentiation
GO:0045582 IMP positive regulation of T cell differentiation
GO:0045987 IMP positive regulation of smooth muscle contraction
GO:0046061 IMP dATP catabolic process
GO:0046101 IMP hypoxanthine biosynthetic process
GO:0046103 IMP inosine biosynthetic process
GO:0046111 IMP xanthine biosynthetic process
GO:0046638 IMP positive regulation of alpha-beta T cell differentiation
GO:0048286 IMP lung alveolus development
GO:0048541 IMP Peyer's patch development
GO:0048566 IMP embryonic digestive tract development
GO:0050728 IMP negative regulation of inflammatory response
GO:0050850 IMP positive regulation of calcium-mediated signaling
GO:0050862 IMP positive regulation of T cell receptor signaling pathway
GO:0050870 IMP positive regulation of T cell activation
GO:0060169 IBA negative regulation of adenosine receptor signaling pathway
GO:0060407 IMP negative regulation of penile erection
GO:0070244 IMP negative regulation of thymocyte apoptotic process
GO:0070256 IGI negative regulation of mucus secretion

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000003113 ada adenosine deaminase protein_coding Danio_rerio
ENSG00000196839 ADA adenosine deaminase protein_coding Homo_sapiens

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