C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: microtubule-associated protein tau
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSMUSG00000018411 Mapt 10090 + 11:104231390-104332090 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENSMUST00000100347 Mapt-007 104231584-104328219 protein_coding
  ENSMUST00000106988 Mapt-002 104282381-104328187 protein_coding
  ENSMUST00000106989 Mapt-003 104282381-104328187 protein_coding
  ENSMUST00000106992 Mapt-001 104231390-104332090 protein_coding
  ENSMUST00000106993 Mapt-006 104231515-104328435 protein_coding
  ENSMUST00000126820 Mapt-010 104321949-104328210 processed_transcript
  ENSMUST00000132245 Mapt-011 104231581-104294924 protein_coding
  ENSMUST00000132977 Mapt-012 104231573-104306758 protein_coding
  ENSMUST00000138384 Mapt-008 104231479-104295317 retained_intron
  ENSMUST00000144836 Mapt-009 104318033-104328241 processed_transcript
  ENSMUST00000145227 Mapt-005 104231484-104306674 protein_coding
  ENSMUST00000146353 Mapt-004 104231579-104306734 processed_transcript

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENSMUST00000100347ENSMUST00000106988ENSMUST00000106989ENSMUST00000106992ENSMUST00000145227
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENSMUST00000100347 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A 0.357±0.00 N/A N/A
ENSMUST00000106988 0.171±0.00 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A
ENSMUST00000106989 N/A N/A N/A N/A 0.176±0.00 0.538±0.00 N/A N/A N/A N/A N/A N/A 0.828±0.40 N/A
ENSMUST00000106992 N/A 27.606±5.80 0.488±0.01 112.883±46.57 0.432±0.07 0.582±0.03 5.272±1.44 22.010±1.30 0.168±0.21 10.533±3.72 2.980±0.00 0.357±0.20 0.263±0.14 0.361±0.00
ENSMUST00000145227 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A 0.954±0.00 N/A N/A

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0004WG CIL_0004WG_0002 CGP 11:104186327-104332090
CIL_0001XT CIL_0001XT_0002 CGP 11:104231390-104468861

Gene Ontology

GO IDEvidence TypeGO Description
GO:0000226 ISS microtubule cytoskeleton organization
GO:0001764 IMP neuron migration
GO:0005515 IPI protein binding
GO:0005634 IDA nucleus
GO:0005737 IDA cytoplasm
GO:0005874 IEA microtubule
GO:0005886 ISS plasma membrane
GO:0005930 IDA axoneme
GO:0007409 IGI axonogenesis
GO:0007628 IGI adult walking behavior
GO:0008017 ISS microtubule binding
GO:0008088 IGI axon cargo transport
GO:0010506 IEA regulation of autophagy
GO:0015630 IDA microtubule cytoskeleton
GO:0017124 IEA SH3 domain binding
GO:0019899 IEA enzyme binding
GO:0019901 IPI protein kinase binding
GO:0030424 ISS axon
GO:0030426 ISS growth cone
GO:0031116 ISS positive regulation of microtubule polymerization
GO:0032387 IMP negative regulation of intracellular transport
GO:0034185 IEA apolipoprotein binding
GO:0034399 IEA nuclear periphery
GO:0036464 IEA cytoplasmic ribonucleoprotein granule
GO:0045298 ISS tubulin complex
GO:0045773 ISS positive regulation of axon extension
GO:0047497 IMP mitochondrion transport along microtubule
GO:0048675 IMP axon extension
GO:0060632 IDA regulation of microtubule-based movement
GO:0071813 IEA lipoprotein particle binding

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000087616 maptb microtubule-associated protein tau b protein_coding Danio_rerio
ENSDARG00000089314 mapta microtubule-associated protein tau a protein_coding Danio_rerio
ENSG00000186868 MAPT microtubule-associated protein tau protein_coding Homo_sapiens

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