C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: KDM1 lysine (K)-specific demethylase 6B
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSMUSG00000018476 Kdm6b 10090 - 11:69398508-69413675 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENSMUST00000094077 Kdm6b-001 69398508-69413675 protein_coding
  ENSMUST00000156562 Kdm6b-002 69403278-69404215 processed_transcript

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENSMUST00000094077
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENSMUST00000094077 4.212±1.14 3.790±0.72 3.289±1.71 7.129±4.62 2.999±2.49 4.881±1.69 0.785±0.66 2.717±0.39 0.946±0.40 5.854±0.89 1.723±0.73 4.451±0.94 5.429±2.28 2.552±1.05

Conserved Regions

Gene is not located within a conserved region.

Gene Ontology
GO IDEvidence TypeGO Description
GO:0005515 IEA protein binding
GO:0005634 IDA nucleus
GO:0006954 IEA inflammatory response
GO:0008013 IPI beta-catenin binding
GO:0016577 IMP histone demethylation
GO:0043565 IDA sequence-specific DNA binding
GO:0045446 IMP endothelial cell differentiation
GO:0045944 IDA positive regulation of transcription from RNA polymerase II promoter
GO:0046872 IEA metal ion binding
GO:0048333 IMP mesodermal cell differentiation
GO:0051213 IEA dioxygenase activity
GO:0055007 IMP cardiac muscle cell differentiation
GO:0055114 IEA oxidation-reduction process
GO:0070301 IDA cellular response to hydrogen peroxide
GO:0071557 IDA histone H3-K27 demethylation
GO:0071558 IDA histone demethylase activity (H3-K27 specific)

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000088087 KDM6B lysine (K)-specific demethylase 6B protein_coding Danio_rerio
ENSG00000132510 KDM6B lysine (K)-specific demethylase 6B protein_coding Homo_sapiens

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