C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: FK506 binding protein 8
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSMUSG00000019428 Fkbp8 10090 + 8:70527724-70535328 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENSMUST00000075491 Fkbp8-002 70527747-70535326 protein_coding
  ENSMUST00000119353 Fkbp8-001 70527724-70535328 protein_coding
  ENSMUST00000119425 Fkbp8-006 70528816-70529583 protein_coding
  ENSMUST00000119698 Fkbp8-003 70527846-70535327 protein_coding
  ENSMUST00000123052 Fkbp8-010 70531734-70534956 retained_intron
  ENSMUST00000125741 Fkbp8-007 70531124-70534171 retained_intron
  ENSMUST00000126613 Fkbp8-009 70532184-70534867 retained_intron
  ENSMUST00000128513 Fkbp8-005 70528009-70530598 retained_intron
  ENSMUST00000134299 Fkbp8-008 70532121-70534971 retained_intron
  ENSMUST00000134893 Fkbp8-011 70534117-70535057 nonsense_mediated_decay
  ENSMUST00000144766 Fkbp8-004 70527762-70532453 retained_intron

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENSMUST00000075491ENSMUST00000119353ENSMUST00000119698ENSMUST00000144766
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENSMUST00000075491 127.317±21.13 144.638±18.93 100.640±15.09 177.660±49.75 92.252±28.52 161.679±25.60 49.479±14.87 141.066±15.63 126.146±33.57 86.048±10.18 50.565±3.67 103.916±23.61 78.588±16.16 82.795±28.17
ENSMUST00000119353 86.380±19.01 100.224±7.67 N/A 80.712±0.00 68.587±11.15 83.126±14.52 28.707±0.00 53.136±0.00 80.205±8.41 51.344±3.21 N/A 70.912±11.74 N/A N/A
ENSMUST00000119698 N/A 77.284±4.14 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A
ENSMUST00000144766 N/A 103.259±2.16 101.569±0.00 N/A N/A N/A N/A N/A N/A N/A N/A 82.465±6.25 N/A N/A

Conserved Regions

Gene is not located within a conserved region.

Gene Ontology
GO IDEvidence TypeGO Description
GO:0000413 IBA protein peptidyl-prolyl isomerization
GO:0001708 IMP cell fate specification
GO:0003755 IBA peptidyl-prolyl cis-trans isomerase activity
GO:0005528 IBA FK506 binding
GO:0005739 IDA mitochondrion
GO:0005740 IDA mitochondrial envelope
GO:0006915 IEA apoptotic process
GO:0007224 IGI smoothened signaling pathway
GO:0009953 IMP dorsal/ventral pattern formation
GO:0010468 IGI regulation of gene expression
GO:0016020 IEA membrane
GO:0021904 IMP dorsal/ventral neural tube patterning
GO:0021915 IMP neural tube development
GO:0030176 IDA integral component of endoplasmic reticulum membrane
GO:0030510 IGI regulation of BMP signaling pathway
GO:0030513 IMP positive regulation of BMP signaling pathway
GO:0035264 IGI multicellular organism growth
GO:0042802 IEA identical protein binding
GO:0043010 IMP camera-type eye development
GO:0043066 IMP negative regulation of apoptotic process
GO:0061077 IBA chaperone-mediated protein folding

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000001734 fkbp8 FK506 binding protein 8 protein_coding Danio_rerio
ENSG00000105701 FKBP8 FK506 binding protein 8, 38kDa protein_coding Homo_sapiens

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