C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: FK506 binding protein 8, 38kDa
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000105701 FKBP8 9606 - 19:18531751-18544077 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000222308 FKBP8-016 18531762-18543524 protein_coding
  ENST00000544835 FKBP8-004 18531752-18543573 protein_coding
  ENST00000594844 FKBP8-007 18539419-18543245 protein_coding
  ENST00000596015 FKBP8-011 18532105-18538371 protein_coding
  ENST00000596494 FKBP8-010 18538076-18539448 retained_intron
  ENST00000596558 FKBP8-002 18531762-18542972 protein_coding
  ENST00000597547 FKBP8-009 18539432-18543483 protein_coding
  ENST00000597611 FKBP8-006 18538216-18544077 protein_coding
  ENST00000597960 FKBP8-001 18531751-18543577 protein_coding
  ENST00000599540 FKBP8-008 18538376-18542498 protein_coding
  ENST00000601844 FKBP8-003 18531814-18543577 nonsense_mediated_decay
  ENST00000606531 FKBP8-015 18532129-18537704 protein_coding
  ENST00000608443 FKBP8-014 18531762-18543660 protein_coding
  ENST00000609656 FKBP8-013 18541902-18544058 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENST00000222308ENST00000594844ENST00000596558ENST00000597547ENST00000597960ENST00000608443
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENST00000222308 106.255±0.00 84.093±0.00 1.876±0.00 156.265±0.00 97.432±0.00 69.659±65.86 36.407±0.00 32.760±0.00 39.488±0.00 106.313±0.00 53.187±0.00 60.880±53.83 84.082±25.56 155.817±29.57
ENST00000594844 N/A N/A N/A 34.326±0.00 N/A N/A 2.977±0.00 6.045±0.00 N/A N/A N/A N/A N/A N/A
ENST00000596558 N/A N/A N/A 13.712±0.00 N/A N/A 1.526±0.00 N/A 4.897±0.00 5.501±0.00 N/A N/A N/A N/A
ENST00000597547 N/A N/A 6.739±0.00 N/A 14.050±0.00 9.737±0.00 N/A 4.727±0.00 12.895±0.00 N/A 4.272±0.00 11.475±0.00 N/A 78.770±0.00
ENST00000597960 N/A N/A N/A N/A N/A 1.598±0.00 N/A N/A N/A N/A N/A 40.844±0.00 N/A 81.533±0.00
ENST00000608443 44.666±0.00 35.375±0.00 5.009±0.00 20.011±0.00 36.143±30.65 17.658±16.38 14.224±12.84 18.986±12.66 24.505±19.79 49.819±0.00 8.804±0.00 35.549±23.05 49.522±13.91 122.900±0.00

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0004NO CIL_0004NO_0002 CGP 19:18442663-18544077

Gene Ontology
GO IDEvidence TypeGO Description
GO:0000413 IEA:IBA protein peptidyl-prolyl isomerization
GO:0001708 IEA cell fate specification
GO:0003755 IEA:IBA peptidyl-prolyl cis-trans isomerase activity
GO:0005515 IPI:IEA protein binding
GO:0005528 IBA FK506 binding
GO:0005739 IEA mitochondrion
GO:0005740 IEA mitochondrial envelope
GO:0005789 IBA endoplasmic reticulum membrane
GO:0006457 IEA protein folding
GO:0006915 IEA apoptotic process
GO:0007224 IEA smoothened signaling pathway
GO:0009953 IEA dorsal/ventral pattern formation
GO:0010468 IEA regulation of gene expression
GO:0016020 IDA membrane
GO:0016032 IEA viral process
GO:0021904 IEA dorsal/ventral neural tube patterning
GO:0021915 IEA neural tube development
GO:0030176 IEA integral component of endoplasmic reticulum membrane
GO:0030510 IEA regulation of BMP signaling pathway
GO:0030513 IEA positive regulation of BMP signaling pathway
GO:0035264 IEA multicellular organism growth
GO:0035556 TAS intracellular signal transduction
GO:0042802 IPI identical protein binding
GO:0043010 IEA camera-type eye development
GO:0043066 IEA negative regulation of apoptotic process
GO:0046872 IEA metal ion binding
GO:0061077 IBA chaperone-mediated protein folding

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000001734 fkbp8 FK506 binding protein 8 protein_coding Danio_rerio
ENSMUSG00000019428 Fkbp8 FK506 binding protein 8 protein_coding Mus_musculus

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