C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: cyclin-dependent kinase 1
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSMUSG00000019942 Cdk1 10090 - 10:69336635-69352938 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENSMUST00000020099 Cdk1-001 69336635-69352938 protein_coding
  ENSMUST00000119827 Cdk1-002 69338324-69352903 protein_coding
  ENSMUST00000123458 Cdk1-007 69340599-69342729 retained_intron
  ENSMUST00000124054 Cdk1-004 69345005-69352910 retained_intron
  ENSMUST00000129444 Cdk1-005 69340730-69345510 retained_intron
  ENSMUST00000149474 Cdk1-006 69340804-69345434 retained_intron
  ENSMUST00000152448 Cdk1-003 69340766-69350830 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENSMUST00000020099ENSMUST00000119827ENSMUST00000123458ENSMUST00000124054ENSMUST00000129444ENSMUST00000149474ENSMUST00000152448
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENSMUST00000020099 0.120±0.00 0.189±0.08 N/A 1.885±0.80 0.147±0.00 0.700±0.07 0.100±0.00 0.070±0.01 1.304±2.73 0.171±0.00 0.044±0.00 0.754±0.00 N/A 0.980±0.00
ENSMUST00000119827 3.442±2.13 0.889±0.29 2.936±0.09 16.075±14.69 1.850±0.75 6.487±0.47 0.389±0.21 0.810±0.22 35.518±42.35 0.935±0.32 0.131±0.13 12.901±7.10 65.630±45.50 10.611±0.49
ENSMUST00000123458 7.839±5.63 2.265±0.03 N/A N/A 2.757±0.60 14.716±3.44 0.394±0.09 0.918±0.03 1.065±0.16 1.642±0.52 0.455±0.00 35.855±9.76 N/A 15.886±1.41
ENSMUST00000124054 N/A N/A 3.963±1.11 21.167±8.82 N/A N/A 0.693±0.00 N/A 94.481±77.01 0.910±0.19 0.153±0.05 15.810±0.00 90.177±25.30 21.740±0.00
ENSMUST00000129444 N/A 0.540±0.00 N/A N/A N/A N/A N/A N/A 0.137±0.00 N/A 0.269±0.00 N/A N/A N/A
ENSMUST00000149474 N/A N/A N/A N/A 0.666±0.00 N/A N/A N/A 0.125±0.01 N/A 0.030±0.00 N/A N/A N/A
ENSMUST00000152448 N/A 1.291±0.50 N/A N/A N/A N/A 0.245±0.07 0.326±0.00 0.195±0.00 0.454±0.00 N/A N/A N/A N/A

Conserved Regions

Gene is not located within a conserved region.

Gene Ontology
GO IDEvidence TypeGO Description
GO:0000278 IEA mitotic cell cycle
GO:0004674 ISS protein serine/threonine kinase activity
GO:0004693 ISS cyclin-dependent protein serine/threonine kinase activity
GO:0005515 IPI protein binding
GO:0005524 IEA ATP binding
GO:0005634 ISO nucleus
GO:0005654 TAS nucleoplasm
GO:0005737 IEA cytoplasm
GO:0005739 IEA mitochondrion
GO:0005813 ISS centrosome
GO:0005876 IEA spindle microtubule
GO:0006461 IEA protein complex assembly
GO:0006468 IDA protein phosphorylation
GO:0006915 IEA apoptotic process
GO:0007067 IEA mitotic nuclear division
GO:0007095 IDA mitotic G2 DNA damage checkpoint
GO:0007569 IEA cell aging
GO:0008353 IEA RNA polymerase II carboxy-terminal domain kinase activity
GO:0009636 IEA response to toxic substance
GO:0010243 IEA response to organonitrogen compound
GO:0010628 IEA positive regulation of gene expression
GO:0014070 IEA response to organic cyclic compound
GO:0014075 IEA response to amine
GO:0014823 IEA response to activity
GO:0016020 IEA membrane
GO:0016301 IDA kinase activity
GO:0016572 IEA histone phosphorylation
GO:0018105 ISS peptidyl-serine phosphorylation
GO:0018107 ISS peptidyl-threonine phosphorylation
GO:0030261 IEA chromosome condensation
GO:0030332 IEA cyclin binding
GO:0030496 IEA midbody
GO:0030544 IPI Hsp70 protein binding
GO:0030855 IEA epithelial cell differentiation
GO:0031100 IEA organ regeneration
GO:0033160 IEA positive regulation of protein import into nucleus, translocation
GO:0034501 IEA protein localization to kinetochore
GO:0035173 IEA histone kinase activity
GO:0042493 IEA response to drug
GO:0042542 IEA response to hydrogen peroxide
GO:0043066 IEA negative regulation of apoptotic process
GO:0045471 IEA response to ethanol
GO:0045740 IEA positive regulation of DNA replication
GO:0045931 IEA positive regulation of mitotic cell cycle
GO:0046686 IEA response to cadmium ion
GO:0046688 IEA response to copper ion
GO:0048678 IEA response to axon injury
GO:0055015 IEA ventricular cardiac muscle cell development
GO:0060045 IEA positive regulation of cardiac muscle cell proliferation
GO:0070062 IEA extracellular vesicular exosome
GO:0070301 IEA cellular response to hydrogen peroxide
GO:0072686 ISS mitotic spindle

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000087554 cdk1 cyclin-dependent kinase 1 protein_coding Danio_rerio
ENSG00000170312 CDK1 cyclin-dependent kinase 1 protein_coding Homo_sapiens

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