C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: connective tissue growth factor
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSMUSG00000019997 Ctgf 10090 + 10:24595442-24598683 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENSMUST00000020171 Ctgf-001 24595442-24598678 protein_coding
  ENSMUST00000129142 Ctgf-002 24595780-24596370 protein_coding
  ENSMUST00000176228 Ctgf-003 24595726-24598683 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENSMUST00000020171ENSMUST00000176228
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENSMUST00000020171 15.382±0.94 113.947±11.36 38.459±17.31 2.832±0.32 22.448±10.17 70.785±5.23 48.531±17.15 57.107±23.66 2.507±1.50 152.081±60.78 9.475±1.40 114.121±54.00 14.867±10.33 7.950±5.35
ENSMUST00000176228 N/A N/A N/A N/A 1.437±0.00 N/A N/A N/A 0.169±0.00 N/A N/A 3.351±0.00 N/A N/A

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_00097U CIL_00097U_0002 VISTA 10:24193263-24794942

Gene Ontology
GO IDEvidence TypeGO Description
GO:0001502 IDA cartilage condensation
GO:0001503 IMP ossification
GO:0001525 IDA angiogenesis
GO:0001558 IEA regulation of cell growth
GO:0001894 IMP tissue homeostasis
GO:0001934 IEA positive regulation of protein phosphorylation
GO:0001968 IEA fibronectin binding
GO:0005178 IDA integrin binding
GO:0005520 IEA insulin-like growth factor binding
GO:0005576 IDA extracellular region
GO:0005578 IDA proteinaceous extracellular matrix
GO:0005615 IEA extracellular space
GO:0005794 IEA Golgi apparatus
GO:0005801 IEA cis-Golgi network
GO:0005829 IEA cytosol
GO:0005938 IEA cell cortex
GO:0007160 IDA cell-matrix adhesion
GO:0007229 IDA integrin-mediated signaling pathway
GO:0008083 IEA growth factor activity
GO:0008201 IDA heparin binding
GO:0008284 IEA positive regulation of cell proliferation
GO:0008543 IDA fibroblast growth factor receptor signaling pathway
GO:0009749 IEA response to glucose
GO:0010260 IEA organ senescence
GO:0010628 IEA positive regulation of gene expression
GO:0010629 IMP negative regulation of gene expression
GO:0010942 IEA positive regulation of cell death
GO:0014070 IEA response to organic cyclic compound
GO:0016477 IDA cell migration
GO:0030154 IDA cell differentiation
GO:0030324 IMP lung development
GO:0032330 IMP regulation of chondrocyte differentiation
GO:0032355 IEA response to estradiol
GO:0032967 IEA positive regulation of collagen biosynthetic process
GO:0034059 IEA response to anoxia
GO:0035556 IEA intracellular signal transduction
GO:0035988 IMP chondrocyte proliferation
GO:0043200 IEA response to amino acid
GO:0043231 IEA intracellular membrane-bounded organelle
GO:0043280 IEA positive regulation of cysteine-type endopeptidase activity involved in apoptotic process
GO:0043434 IEA response to peptide hormone
GO:0045597 IEA positive regulation of cell differentiation
GO:0046330 IEA positive regulation of JNK cascade
GO:0048471 IEA perinuclear region of cytoplasm
GO:0050867 IEA positive regulation of cell activation
GO:0051385 IEA response to mineralocorticoid
GO:0051496 IEA positive regulation of stress fiber assembly
GO:0060401 IEA cytosolic calcium ion transport
GO:0060452 IEA positive regulation of cardiac muscle contraction
GO:0060548 IEA negative regulation of cell death
GO:0061448 IMP connective tissue development
GO:0070278 IEA extracellular matrix constituent secretion
GO:0070318 IEA positive regulation of G0 to G1 transition
GO:0070374 IEA positive regulation of ERK1 and ERK2 cascade
GO:0070542 IEA response to fatty acid
GO:0071897 IEA DNA biosynthetic process
GO:0072593 IDA reactive oxygen species metabolic process

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000042934 ctgfa connective tissue growth factor a protein_coding Danio_rerio
ENSG00000118523 CTGF connective tissue growth factor protein_coding Homo_sapiens

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