C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: apoptosis-inducing factor, mitochondrion-associated 2
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSMUSG00000020085 Aifm2 10090 + 10:61715263-61739260 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENSMUST00000067857 Aifm2-002 61715311-61739260 protein_coding
  ENSMUST00000080099 Aifm2-004 61720649-61738653 protein_coding
  ENSMUST00000099706 Aifm2-003 61715323-61738647 protein_coding
  ENSMUST00000105455 Aifm2-001 61715263-61738653 protein_coding
  ENSMUST00000129809 Aifm2-007 61715332-61716235 processed_transcript
  ENSMUST00000131361 Aifm2-005 61715287-61727921 retained_intron
  ENSMUST00000140664 Aifm2-006 61728148-61734570 retained_intron

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENSMUST00000080099ENSMUST00000099706ENSMUST00000105455
Transcript ID Adipose Adrenal Bladder Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENSMUST00000080099 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A 1.541±0.00 1.839±0.00
ENSMUST00000099706 54.467±31.33 87.032±13.88 49.585±31.57 34.902±5.48 3.223±0.67 10.973±1.67 8.290±0.27 3.725±2.33 6.485±0.81 3.537±0.56 10.201±3.34 4.462±5.05 3.507±1.94
ENSMUST00000105455 21.099±10.36 51.097±6.35 N/A 15.061±0.82 2.921±0.82 4.328±0.33 4.224±0.59 2.937±1.63 2.987±0.48 4.256±0.54 8.248±2.54 1.697±0.23 5.380±2.62

Conserved Regions

Gene is not located within a conserved region.

Gene Ontology
GO IDEvidence TypeGO Description
GO:0003677 ISS DNA binding
GO:0004174 ISS electron-transferring-flavoprotein dehydrogenase activity
GO:0005615 IEA extracellular space
GO:0005737 IEA cytoplasm
GO:0005739 IDA mitochondrion
GO:0005741 ISS mitochondrial outer membrane
GO:0005811 IEA lipid particle
GO:0005829 ISS cytosol
GO:0008137 IBA NADH dehydrogenase (ubiquinone) activity
GO:0008637 IEA apoptotic mitochondrial changes
GO:0016021 IEA integral component of membrane
GO:0043065 ISS positive regulation of apoptotic process
GO:0050660 ISS flavin adenine dinucleotide binding
GO:0055114 IEA oxidation-reduction process

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000077549 AIFM2 apoptosis-inducing factor, mitochondrion-associated, 2 protein_coding Danio_rerio
ENSG00000042286 AIFM2 apoptosis-inducing factor, mitochondrion-associated, 2 protein_coding Homo_sapiens

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