C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: apoptosis-inducing factor, mitochondrion-associated, 2
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000042286 AIFM2 9606 - 10:70098223-70132934 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000307864 AIFM2-001 70112271-70132934 protein_coding
  ENST00000373248 AIFM2-002 70098223-70124102 protein_coding
  ENST00000482166 AIFM2-003 70114775-70118351 processed_transcript
  ENST00000613322 AIFM2-201 70112270-70132934 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENST00000307864ENST00000373248ENST00000613322
Transcript ID Adipose Adrenal Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENST00000307864 17.072±0.00 3.095±0.00 1.149±0.78 22.253±20.50 4.004±0.00 3.031±0.00 7.646±0.00 3.286±2.70 2.243±1.88 2.059±0.00 6.078±2.71 3.079±0.38 3.193±0.68
ENST00000373248 N/A N/A N/A N/A N/A 0.174±0.00 N/A N/A N/A 1.107±0.00 N/A N/A N/A
ENST00000613322 6.247±0.00 1.739±0.00 0.351±0.00 13.745±0.00 2.685±0.00 1.568±0.00 N/A 0.586±0.00 0.359±0.00 N/A N/A 1.871±0.00 1.441±0.00

Conserved Regions

Gene is not located within a conserved region.

Gene Ontology
GO IDEvidence TypeGO Description
GO:0003677 IDA DNA binding
GO:0004174 IDA electron-transferring-flavoprotein dehydrogenase activity
GO:0005615 IDA extracellular space
GO:0005737 IDA cytoplasm
GO:0005739 IDA mitochondrion
GO:0005741 IDA mitochondrial outer membrane
GO:0005811 IDA lipid particle
GO:0005829 IDA cytosol
GO:0008137 IBA NADH dehydrogenase (ubiquinone) activity
GO:0008637 IDA apoptotic mitochondrial changes
GO:0016021 IEA integral component of membrane
GO:0016491 IEA oxidoreductase activity
GO:0043065 IBA positive regulation of apoptotic process
GO:0050660 IDA:IEA flavin adenine dinucleotide binding
GO:0055114 IEA oxidation-reduction process

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000077549 AIFM2 apoptosis-inducing factor, mitochondrion-associated, 2 protein_coding Danio_rerio
ENSMUSG00000020085 Aifm2 apoptosis-inducing factor, mitochondrion-associated 2 protein_coding Mus_musculus

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