C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: DNA-damage-inducible transcript 4
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSMUSG00000020108 Ddit4 10090 - 10:59949675-59951770 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENSMUST00000020308 Ddit4-201 59949675-59951770 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENSMUST00000020308
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENSMUST00000020308 15.898±9.29 60.827±4.33 11.394±3.58 21.900±7.69 23.567±13.65 48.008±5.53 12.006±6.90 7.006±1.94 5.397±2.14 16.950±4.87 7.498±5.00 35.028±12.11 15.422±6.07 7.542±1.97

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0007VS CIL_0007VS_0002 VISTA 10:59667734-60271225

Gene Ontology
GO IDEvidence TypeGO Description
GO:0001666 IMP response to hypoxia
GO:0001764 ISS neuron migration
GO:0005622 IEA intracellular
GO:0005737 ISS cytoplasm
GO:0005739 IDA mitochondrion
GO:0007420 ISS brain development
GO:0008283 ISS cell proliferation
GO:0010801 ISS negative regulation of peptidyl-threonine phosphorylation
GO:0030182 ISS neuron differentiation
GO:0032007 IMP negative regulation of TOR signaling
GO:0033137 ISS negative regulation of peptidyl-serine phosphorylation
GO:0042771 IMP intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator
GO:0043241 IMP protein complex disassembly
GO:0045820 IMP negative regulation of glycolytic process
GO:0048011 ISS neurotrophin TRK receptor signaling pathway
GO:0051607 IEA defense response to virus
GO:0071889 IDA 14-3-3 protein binding
GO:0072593 IMP reactive oxygen species metabolic process
GO:1901216 ISS positive regulation of neuron death
GO:1902532 ISS negative regulation of intracellular signal transduction

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000037618 ddit4 DNA-damage-inducible transcript 4 protein_coding Danio_rerio
ENSG00000168209 DDIT4 DNA-damage-inducible transcript 4 protein_coding Homo_sapiens

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