C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: MAP kinase-interacting serine/threonine kinase 2
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSMUSG00000020190 Mknk2 10090 - 10:80665332-80671976 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENSMUST00000003433 Mknk2-201 80665332-80671976 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENSMUST00000003433
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENSMUST00000003433 178.452±100.15 107.602±41.38 50.260±12.48 23.541±6.86 210.467±59.68 100.604±26.99 33.347±9.27 41.246±10.65 37.832±10.48 80.307±21.76 31.529±17.52 62.939±28.28 24.613±6.30 17.688±5.10

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_00018B CIL_00018B_0002 CGP 10:80642617-80671976
CIL_00018A CIL_00018A_0002 CGP 10:80665332-80701820

Gene Ontology
GO IDEvidence TypeGO Description
GO:0004674 IDA protein serine/threonine kinase activity
GO:0005515 IPI protein binding
GO:0005524 IDA ATP binding
GO:0005634 IEA nucleus
GO:0005730 IEA nucleolus
GO:0005737 IEA cytoplasm
GO:0006417 IEA regulation of translation
GO:0006468 IDA protein phosphorylation
GO:0030097 IEA hemopoiesis
GO:0035556 IDA intracellular signal transduction
GO:0046872 IEA metal ion binding
GO:0071243 IEA cellular response to arsenic-containing substance
GO:0097192 IGI extrinsic apoptotic signaling pathway in absence of ligand

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000011373 mknk2a MAP kinase-interacting serine/threonine kinase 2a protein_coding Danio_rerio
ENSDARG00000015164 mknk2b MAP kinase-interacting serine/threonine kinase 2b protein_coding Danio_rerio
ENSG00000099875 MKNK2 MAP kinase interacting serine/threonine kinase 2 protein_coding Homo_sapiens

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