C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: phosphofructokinase, liver, B-type
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSMUSG00000020277 Pfkl 10090 - 10:77986947-78010083 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENSMUST00000020522 Pfkl-001 77986947-78009807 protein_coding
  ENSMUST00000145716 Pfkl-004 78000680-78010083 processed_transcript
  ENSMUST00000148818 Pfkl-002 77997237-77999934 retained_intron
  ENSMUST00000149271 Pfkl-003 77990463-77992176 retained_intron

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENSMUST00000020522
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENSMUST00000020522 25.223±2.20 39.718±6.83 9.719±1.33 23.447±18.99 36.909±12.23 56.850±15.00 20.949±2.05 25.312±3.30 13.331±5.47 21.525±0.84 2.051±0.44 31.885±16.83 15.206±4.92 4.534±2.00

Conserved Regions

Gene is not located within a conserved region.

Gene Ontology
GO IDEvidence TypeGO Description
GO:0003872 IDA 6-phosphofructokinase activity
GO:0005515 IEA protein binding
GO:0005829 IDA cytosol
GO:0005945 IEA 6-phosphofructokinase complex
GO:0005975 IEA carbohydrate metabolic process
GO:0006002 IDA fructose 6-phosphate metabolic process
GO:0006096 IEA glycolytic process
GO:0009749 IDA response to glucose
GO:0016020 IEA membrane
GO:0019900 IEA kinase binding
GO:0030388 ISS fructose 1,6-bisphosphate metabolic process
GO:0042802 IEA identical protein binding
GO:0046676 IDA negative regulation of insulin secretion
GO:0046835 IEA carbohydrate phosphorylation
GO:0046872 IEA metal ion binding
GO:0048029 IEA monosaccharide binding
GO:0051259 IEA protein oligomerization
GO:0051289 IEA protein homotetramerization
GO:0070061 IEA fructose binding
GO:0070062 IEA extracellular vesicular exosome
GO:0070095 IEA fructose-6-phosphate binding

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000042375 pfklb phosphofructokinase, liver b protein_coding Danio_rerio
ENSDARG00000060504 PFKL (2 of 2) phosphofructokinase, liver protein_coding Danio_rerio
ENSG00000141959 PFKL phosphofructokinase, liver protein_coding Homo_sapiens

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