C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: protein phosphatase 2 (formerly 2A), catalytic subunit, alpha isoform
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSMUSG00000020349 Ppp2ca 10090 + 11:52098681-52127778 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENSMUST00000020608 Ppp2ca-001 52098681-52127778 protein_coding
  ENSMUST00000142939 Ppp2ca-002 52118743-52119692 retained_intron

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENSMUST00000020608
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENSMUST00000020608 27.553±3.00 22.563±7.76 22.579±1.07 24.527±13.53 26.439±4.73 30.605±4.48 18.252±1.67 18.852±1.98 17.272±5.50 23.377±2.67 9.997±4.50 20.685±6.66 17.291±5.68 4.398±1.89

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_00089W CIL_00089W_0002 VISTA 11:51640537-52246109

Gene Ontology
GO IDEvidence TypeGO Description
GO:0000159 IDA protein phosphatase type 2A complex
GO:0000775 IDA chromosome, centromeric region
GO:0001932 ISO regulation of protein phosphorylation
GO:0004722 TAS protein serine/threonine phosphatase activity
GO:0005515 IPI protein binding
GO:0005634 IEA nucleus
GO:0005737 IDA cytoplasm
GO:0005829 IDA cytosol
GO:0005856 IEA cytoskeleton
GO:0005886 IDA plasma membrane
GO:0006470 TAS protein dephosphorylation
GO:0007498 IMP mesoderm development
GO:0008022 IPI protein C-terminus binding
GO:0010469 ISO regulation of receptor activity
GO:0010719 IEA negative regulation of epithelial to mesenchymal transition
GO:0031952 ISO regulation of protein autophosphorylation
GO:0042176 ISO regulation of protein catabolic process
GO:0046872 IEA metal ion binding
GO:0046982 ISS protein heterodimerization activity
GO:0046983 ISO protein dimerization activity
GO:0050811 IDA GABA receptor binding
GO:0051321 IEA meiotic cell cycle
GO:0051726 TAS regulation of cell cycle
GO:0070062 IEA extracellular vesicular exosome
GO:0070208 ISO protein heterotrimerization
GO:0071902 IEA positive regulation of protein serine/threonine kinase activity

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000030224 ppp2ca protein phosphatase 2 (formerly 2A), catalytic subunit, alpha isoform protein_coding Danio_rerio
ENSDARG00000053404 PPP2CA protein phosphatase 2, catalytic subunit, alpha isozyme protein_coding Danio_rerio
ENSG00000113575 PPP2CA protein phosphatase 2, catalytic subunit, alpha isozyme protein_coding Homo_sapiens

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