C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: RAD50 homolog (S. cerevisiae)
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSMUSG00000020380 Rad50 10090 - 11:53649519-53707319 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENSMUST00000020649 Rad50-001 53649519-53707319 protein_coding
  ENSMUST00000124352 Rad50-005 53683255-53707295 protein_coding
  ENSMUST00000126121 Rad50-004 53678835-53680212 processed_transcript
  ENSMUST00000128483 Rad50-002 53674755-53707319 nonsense_mediated_decay
  ENSMUST00000152598 Rad50-003 53691921-53695000 processed_transcript

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENSMUST00000020649ENSMUST00000128483
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENSMUST00000020649 1.488±0.73 3.802±0.63 4.642±1.63 1.742±0.20 3.231±2.02 1.887±0.99 0.428±0.28 1.232±0.51 2.834±1.98 3.068±2.02 0.558±0.14 7.124±7.05 3.649±1.08 0.278±0.00
ENSMUST00000128483 1.037±0.00 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A

Conserved Regions

Gene is not located within a conserved region.

Gene Ontology
GO IDEvidence TypeGO Description
GO:0000014 IEA single-stranded DNA endodeoxyribonuclease activity
GO:0000019 IEA regulation of mitotic recombination
GO:0000737 IEA DNA catabolic process, endonucleolytic
GO:0000784 IEA nuclear chromosome, telomeric region
GO:0003677 IEA DNA binding
GO:0004003 IEA ATP-dependent DNA helicase activity
GO:0004518 IEA nuclease activity
GO:0005515 IEA protein binding
GO:0005524 IEA ATP binding
GO:0005634 IDA nucleus
GO:0006281 IEA DNA repair
GO:0006302 IEA double-strand break repair
GO:0006310 IEA DNA recombination
GO:0006974 ISO cellular response to DNA damage stimulus
GO:0007004 IEA telomere maintenance via telomerase
GO:0008270 IEA zinc ion binding
GO:0008408 IEA 3'-5' exonuclease activity
GO:0016020 IEA membrane
GO:0030674 IEA protein binding, bridging
GO:0030870 IEA Mre11 complex
GO:0031954 IEA positive regulation of protein autophosphorylation
GO:0032508 IEA DNA duplex unwinding
GO:0033674 IEA positive regulation of kinase activity
GO:0035861 IEA site of double-strand break
GO:0045120 IDA pronucleus
GO:0090305 IEA nucleic acid phosphodiester bond hydrolysis

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000038917 rad50 RAD50 homolog (S. cerevisiae) protein_coding Danio_rerio
ENSG00000113522 RAD50 RAD50 homolog (S. cerevisiae) protein_coding Homo_sapiens

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