C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: ubiquitin-conjugating enzyme E2B
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSMUSG00000020390 Ube2b 10090 - 11:51985497-52000762 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENSMUST00000020657 Ube2b-001 51985497-52000484 protein_coding
  ENSMUST00000109086 Ube2b-002 51986667-52000762 protein_coding
  ENSMUST00000124699 Ube2b-003 51997570-52000479 processed_transcript
  ENSMUST00000147833 Ube2b-004 51997646-52000762 processed_transcript

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENSMUST00000020657ENSMUST00000109086ENSMUST00000124699
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENSMUST00000020657 11.801±1.34 13.912±3.23 50.671±5.96 33.546±17.96 20.688±7.00 10.966±2.38 49.273±3.54 18.659±3.58 24.676±5.24 19.483±1.07 173.053±18.57 12.356±13.90 26.713±11.27 18.066±8.38
ENSMUST00000109086 38.216±1.77 69.001±8.22 47.889±8.98 N/A 40.395±15.72 28.758±2.62 71.310±5.68 23.147±1.98 29.123±9.69 27.673±4.38 102.299±0.00 30.299±3.71 32.276±13.54 81.808±34.09
ENSMUST00000124699 N/A 11.530±0.00 N/A N/A N/A N/A N/A N/A N/A N/A N/A 8.354±0.00 N/A N/A

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_00089W CIL_00089W_0002 VISTA 11:51640537-52246109
CIL_0007JT CIL_0007JT_0003 UCNEbase 11:51813690-51986519

Gene Ontology
GO IDEvidence TypeGO Description
GO:0000209 IEA protein polyubiquitination
GO:0000785 IDA chromatin
GO:0000790 IDA nuclear chromatin
GO:0001666 IEA response to hypoxia
GO:0001701 IGI in utero embryonic development
GO:0001741 IDA XY body
GO:0004842 ISS ubiquitin-protein transferase activity
GO:0005515 IPI protein binding
GO:0005524 IEA ATP binding
GO:0005634 IEA nucleus
GO:0005657 IEA replication fork
GO:0005737 IEA cytoplasm
GO:0005886 IEA plasma membrane
GO:0006281 IEA DNA repair
GO:0006301 IEA postreplication repair
GO:0006344 IMP maintenance of chromatin silencing
GO:0006511 IEA ubiquitin-dependent protein catabolic process
GO:0006513 IEA protein monoubiquitination
GO:0006974 IEA cellular response to DNA damage stimulus
GO:0007283 IMP spermatogenesis
GO:0007288 IMP sperm axoneme assembly
GO:0009411 IEA response to UV
GO:0010845 IMP positive regulation of reciprocal meiotic recombination
GO:0016567 IEA protein ubiquitination
GO:0016881 IEA acid-amino acid ligase activity
GO:0031056 IMP regulation of histone modification
GO:0031625 IEA ubiquitin protein ligase binding
GO:0032869 IEA cellular response to insulin stimulus
GO:0033128 IMP negative regulation of histone phosphorylation
GO:0033503 ISS HULC complex
GO:0033522 IEA histone H2A ubiquitination
GO:0042493 IEA response to drug
GO:0043066 IMP negative regulation of apoptotic process
GO:0043161 IEA proteasome-mediated ubiquitin-dependent protein catabolic process
GO:0043951 IEA negative regulation of cAMP-mediated signaling
GO:0050821 IEA protein stabilization
GO:0051026 IMP chiasma assembly
GO:0051865 IEA protein autoubiquitination
GO:0060070 IMP canonical Wnt signaling pathway
GO:0070076 IMP histone lysine demethylation
GO:0070193 IMP synaptonemal complex organization
GO:0070534 ISS protein K63-linked ubiquitination
GO:0070936 ISS protein K48-linked ubiquitination
GO:0070979 ISS protein K11-linked ubiquitination

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSG00000119048 UBE2B ubiquitin-conjugating enzyme E2B protein_coding Homo_sapiens

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