C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: ubiquitin-conjugating enzyme E2B
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000119048 UBE2B 9606 + 5:134371179-134391992 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000265339 UBE2B-001 134371179-134391992 protein_coding
  ENST00000499038 UBE2B-007 134385603-134390783 processed_transcript
  ENST00000503080 UBE2B-006 134388138-134390605 retained_intron
  ENST00000504431 UBE2B-002 134371606-134374583 retained_intron
  ENST00000506787 UBE2B-005 134371599-134390321 protein_coding
  ENST00000507277 UBE2B-008 134371604-134390573 protein_coding
  ENST00000510021 UBE2B-004 134371469-134390298 nonsense_mediated_decay
  ENST00000511807 UBE2B-003 134371502-134390436 processed_transcript

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENST00000265339ENST00000499038ENST00000506787ENST00000507277ENST00000511807
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENST00000265339 5.481±0.00 2.967±0.00 0.901±0.00 4.127±0.00 4.467±2.71 9.863±0.00 5.063±4.00 8.341±0.00 2.048±0.49 9.006±0.00 14.445±0.00 4.286±3.17 3.802±1.29 6.011±3.41
ENST00000499038 17.160±0.00 8.270±0.00 N/A 5.543±1.70 17.845±0.00 15.376±11.77 13.983±0.00 23.496±0.00 9.367±0.00 27.345±0.00 32.956±0.00 9.646±7.44 13.164±6.87 17.101±12.25
ENST00000506787 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A 9.296±0.00 9.643±0.00 13.963±0.00
ENST00000507277 22.912±0.00 14.317±0.00 N/A 12.033±0.00 21.008±0.00 27.164±0.00 16.133±14.10 7.061±5.79 7.675±0.00 33.689±0.00 47.943±0.00 15.893±5.11 10.959±1.09 15.398±3.24
ENST00000511807 N/A N/A 3.393±0.00 N/A 3.660±0.00 4.819±0.00 N/A N/A 2.877±0.00 6.750±0.00 N/A 4.943±0.00 N/A N/A

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_00089W CIL_00089W_0001 VISTA 5:134136326-134739629

Gene Ontology
GO IDEvidence TypeGO Description
GO:0000209 IMP protein polyubiquitination
GO:0000785 ISS chromatin
GO:0000790 IEA nuclear chromatin
GO:0001666 IEA response to hypoxia
GO:0001701 IEA in utero embryonic development
GO:0001741 IEA XY body
GO:0004842 IDA ubiquitin-protein transferase activity
GO:0005515 IPI protein binding
GO:0005524 IEA ATP binding
GO:0005634 IDA nucleus
GO:0005657 IDA replication fork
GO:0005737 IDA cytoplasm
GO:0005886 IEA plasma membrane
GO:0006281 IGI DNA repair
GO:0006301 IDA postreplication repair
GO:0006344 IEA maintenance of chromatin silencing
GO:0006511 IDA ubiquitin-dependent protein catabolic process
GO:0006513 IMP protein monoubiquitination
GO:0006974 IDA cellular response to DNA damage stimulus
GO:0007283 TAS spermatogenesis
GO:0007288 IEA sperm axoneme assembly
GO:0008152 IEA metabolic process
GO:0009411 IGI response to UV
GO:0010845 IEA positive regulation of reciprocal meiotic recombination
GO:0016567 IDA protein ubiquitination
GO:0016881 IEA acid-amino acid ligase activity
GO:0031056 IEA regulation of histone modification
GO:0031625 IPI ubiquitin protein ligase binding
GO:0032869 IEA cellular response to insulin stimulus
GO:0033128 IEA negative regulation of histone phosphorylation
GO:0033503 IDA HULC complex
GO:0033522 IMP histone H2A ubiquitination
GO:0042493 IDA response to drug
GO:0043066 IEA negative regulation of apoptotic process
GO:0043161 IDA proteasome-mediated ubiquitin-dependent protein catabolic process
GO:0043951 IDA negative regulation of cAMP-mediated signaling
GO:0050821 IMP protein stabilization
GO:0051026 IEA chiasma assembly
GO:0051865 IDA protein autoubiquitination
GO:0060070 ISS canonical Wnt signaling pathway
GO:0070076 IEA histone lysine demethylation
GO:0070193 IEA synaptonemal complex organization
GO:0070534 IDA protein K63-linked ubiquitination
GO:0070936 IDA protein K48-linked ubiquitination
GO:0070979 IDA protein K11-linked ubiquitination

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSMUSG00000020390 Ube2b ubiquitin-conjugating enzyme E2B protein_coding Mus_musculus

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