C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: polyribonucleotide nucleotidyltransferase 1
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSMUSG00000020464 Pnpt1 10090 + 11:29130744-29161828 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENSMUST00000020756 Pnpt1-001 29130748-29161828 protein_coding
  ENSMUST00000131527 Pnpt1-004 29138187-29145470 processed_transcript
  ENSMUST00000148173 Pnpt1-003 29130748-29135563 processed_transcript
  ENSMUST00000154924 Pnpt1-002 29130744-29161680 processed_transcript

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENSMUST00000020756ENSMUST00000148173ENSMUST00000154924
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENSMUST00000020756 2.834±1.12 5.070±1.95 5.371±2.16 4.455±0.30 3.483±0.54 2.950±0.24 2.865±1.05 4.909±1.44 12.109±7.72 3.007±0.43 3.034±0.78 8.176±1.79 11.498±5.39 3.089±1.22
ENSMUST00000148173 N/A 9.964±3.43 N/A 17.643±0.00 3.251±0.99 4.665±1.77 N/A 2.736±0.00 3.322±0.43 2.264±0.00 N/A 9.963±14.03 54.579±27.38 9.759±6.43
ENSMUST00000154924 0.767±0.26 1.598±0.00 2.021±0.16 1.725±1.21 0.700±0.32 0.492±0.00 0.507±0.02 N/A 1.690±0.71 N/A 0.444±0.08 2.038±0.46 1.609±0.48 0.691±0.00

Conserved Regions

Gene is not located within a conserved region.

Gene Ontology
GO IDEvidence TypeGO Description
GO:0000175 ISS 3'-5'-exoribonuclease activity
GO:0000957 ISS mitochondrial RNA catabolic process
GO:0000958 IMP mitochondrial mRNA catabolic process
GO:0000962 ISS positive regulation of mitochondrial RNA catabolic process
GO:0000964 ISS mitochondrial RNA 5'-end processing
GO:0000965 ISS mitochondrial RNA 3'-end processing
GO:0004654 ISS polyribonucleotide nucleotidyltransferase activity
GO:0005515 IEA protein binding
GO:0005737 IEA cytoplasm
GO:0005739 IDA mitochondrion
GO:0005758 IDA mitochondrial intermembrane space
GO:0006401 ISS RNA catabolic process
GO:0006402 ISS mRNA catabolic process
GO:0008266 ISS poly(U) RNA binding
GO:0016020 IEA membrane
GO:0034046 ISS poly(G) binding
GO:0034599 ISS cellular response to oxidative stress
GO:0035198 ISS miRNA binding
GO:0035458 IEA cellular response to interferon-beta
GO:0035927 ISS RNA import into mitochondrion
GO:0035928 ISS rRNA import into mitochondrion
GO:0043457 IMP regulation of cellular respiration
GO:0043631 ISS RNA polyadenylation
GO:0044822 IEA poly(A) RNA binding
GO:0045025 ISS mitochondrial degradosome
GO:0045926 ISS negative regulation of growth
GO:0051260 ISS protein homooligomerization
GO:0061014 ISS positive regulation of mRNA catabolic process
GO:0070207 ISS protein homotrimerization
GO:0070584 IMP mitochondrion morphogenesis
GO:0071042 ISS nuclear polyadenylation-dependent mRNA catabolic process
GO:0071850 ISS mitotic cell cycle arrest
GO:0090503 IEA RNA phosphodiester bond hydrolysis, exonucleolytic
GO:0097222 ISS mitochondrial mRNA polyadenylation
GO:2000627 ISS positive regulation of miRNA catabolic process
GO:2000772 ISS regulation of cellular senescence

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSG00000138035 PNPT1 polyribonucleotide nucleotidyltransferase 1 protein_coding Homo_sapiens

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