C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Transcript Info
Description: polyribonucleotide nucleotidyltransferase 1
Transcript Accession Transcript Name Contained in Gene Tax ID Strand Position Biotype
ENSMUST00000020756 Pnpt1-001 ENSMUSG00000020464 10090 + 11:29130748-29161828 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENSMUST00000020756
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENSMUST00000020756 2.834±1.12 5.070±1.95 5.371±2.16 4.455±0.30 3.483±0.54 2.950±0.24 2.865±1.05 4.909±1.44 12.109±7.72 3.007±0.43 3.034±0.78 8.176±1.79 11.498±5.39 3.089±1.22

Conserved Regions

Gene is not located within a conserved region.

Gene Ontology

GO IDEvidence TypeGO Description
GO:0000175 ISS 3'-5'-exoribonuclease activity
GO:0000957 ISS mitochondrial RNA catabolic process
GO:0000958 IMP mitochondrial mRNA catabolic process
GO:0000962 ISS positive regulation of mitochondrial RNA catabolic process
GO:0000964 ISS mitochondrial RNA 5'-end processing
GO:0000965 ISS mitochondrial RNA 3'-end processing
GO:0004654 ISS polyribonucleotide nucleotidyltransferase activity
GO:0005515 IEA protein binding
GO:0005737 IEA cytoplasm
GO:0005739 IDA mitochondrion
GO:0005758 IDA mitochondrial intermembrane space
GO:0006401 ISS RNA catabolic process
GO:0006402 ISS mRNA catabolic process
GO:0008266 ISS poly(U) RNA binding
GO:0016020 IEA membrane
GO:0034046 ISS poly(G) binding
GO:0034599 ISS cellular response to oxidative stress
GO:0035198 ISS miRNA binding
GO:0035458 IEA cellular response to interferon-beta
GO:0035927 ISS RNA import into mitochondrion
GO:0035928 ISS rRNA import into mitochondrion
GO:0043457 IMP regulation of cellular respiration
GO:0043631 ISS RNA polyadenylation
GO:0044822 IEA poly(A) RNA binding
GO:0045025 ISS mitochondrial degradosome
GO:0045926 ISS negative regulation of growth
GO:0051260 ISS protein homooligomerization
GO:0061014 ISS positive regulation of mRNA catabolic process
GO:0070207 ISS protein homotrimerization
GO:0070584 IMP mitochondrion morphogenesis
GO:0071042 ISS nuclear polyadenylation-dependent mRNA catabolic process
GO:0071850 ISS mitotic cell cycle arrest
GO:0090503 IEA RNA phosphodiester bond hydrolysis, exonucleolytic
GO:0097222 ISS mitochondrial mRNA polyadenylation
GO:2000627 ISS positive regulation of miRNA catabolic process
GO:2000772 ISS regulation of cellular senescence

Homologs

ENSEMBL Accession Gene Name Biotype Species E-Value Bit Score
ENST00000260604 PNPT1-004 nonsense_mediated_decay Homo_sapiens 0 2218
ENST00000415374 PNPT1-007 nonsense_mediated_decay Homo_sapiens 0 2695
ENST00000415489 PNPT1-008 nonsense_mediated_decay Homo_sapiens 0 472
ENST00000429805 PNPT1-003 nonsense_mediated_decay Homo_sapiens 0 448
ENST00000447944 PNPT1-001 protein_coding Homo_sapiens 0 2708
ENST00000450418 PNPT1P1-001 processed_pseudogene Homo_sapiens 0 2453
ENST00000481066 PNPT1-005 retained_intron Homo_sapiens 0 488
ENST00000619878 PNPT1-201 protein_coding Homo_sapiens 0 2702

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