C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: inhibitor of DNA binding 2
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSMUSG00000020644 Id2 10090 - 12:25093801-25096092 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENSMUST00000020974 Id2-201 25093801-25096092 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENSMUST00000020974
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENSMUST00000020974 41.205±32.68 396.962±24.71 134.286±8.60 38.323±8.39 43.545±17.15 31.885±7.85 12.007±1.99 287.995±41.50 87.851±43.51 70.674±31.40 2.064±0.48 106.291±39.66 42.541±20.89 5.556±3.04

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_00099S CIL_00099S_0002 VISTA 12:24823955-25426084
CIL_0005Z9 CIL_0005Z9_0002 CGP 12:24974932-25096092
CIL_00067Q CIL_00067Q_0002 CGP 12:25093801-26415256

Gene Ontology
GO IDEvidence TypeGO Description
GO:0000122 IGI negative regulation of transcription from RNA polymerase II promoter
GO:0000785 IEA chromatin
GO:0001656 IMP metanephros development
GO:0001779 IGI natural killer cell differentiation
GO:0002521 IMP leukocyte differentiation
GO:0003149 IMP membranous septum morphogenesis
GO:0003166 IMP bundle of His development
GO:0005515 IPI protein binding
GO:0005634 IDA nucleus
GO:0005737 IDA cytoplasm
GO:0005813 IEA centrosome
GO:0005829 IEA cytosol
GO:0006351 IEA transcription, DNA-templated
GO:0007507 IGI heart development
GO:0007623 IEP circadian rhythm
GO:0008284 IEA positive regulation of cell proliferation
GO:0009649 IMP entrainment of circadian clock
GO:0010628 IMP positive regulation of gene expression
GO:0010629 IMP negative regulation of gene expression
GO:0014003 IMP oligodendrocyte development
GO:0019216 IMP regulation of lipid metabolic process
GO:0021772 IMP olfactory bulb development
GO:0032922 IMP circadian regulation of gene expression
GO:0033598 IMP mammary gland epithelial cell proliferation
GO:0042752 IMP regulation of circadian rhythm
GO:0043153 IMP entrainment of circadian clock by photoperiod
GO:0043234 IDA protein complex
GO:0043353 IGI enucleate erythrocyte differentiation
GO:0043392 IDA negative regulation of DNA binding
GO:0043433 IEA negative regulation of sequence-specific DNA binding transcription factor activity
GO:0044325 IEA ion channel binding
GO:0045475 IMP locomotor rhythm
GO:0045578 IMP negative regulation of B cell differentiation
GO:0045600 IMP positive regulation of fat cell differentiation
GO:0045648 IMP positive regulation of erythrocyte differentiation
GO:0045651 IGI positive regulation of macrophage differentiation
GO:0045665 IMP negative regulation of neuron differentiation
GO:0045668 IGI negative regulation of osteoblast differentiation
GO:0045777 IMP positive regulation of blood pressure
GO:0045787 IEA positive regulation of cell cycle
GO:0045892 IMP negative regulation of transcription, DNA-templated
GO:0045893 IMP positive regulation of transcription, DNA-templated
GO:0046983 IEA protein dimerization activity
GO:0048468 IGI cell development
GO:0048469 IMP cell maturation
GO:0048535 TAS lymph node development
GO:0048541 IGI Peyer's patch development
GO:0048557 IDA embryonic digestive tract morphogenesis
GO:0048661 IMP positive regulation of smooth muscle cell proliferation
GO:0048663 IMP neuron fate commitment
GO:0048711 IMP positive regulation of astrocyte differentiation
GO:0048715 IMP negative regulation of oligodendrocyte differentiation
GO:0060612 IMP adipose tissue development
GO:0060749 IMP mammary gland alveolus development
GO:0061030 IMP epithelial cell differentiation involved in mammary gland alveolus development
GO:0061031 IEP endodermal digestive tract morphogenesis
GO:0071158 IMP positive regulation of cell cycle arrest
GO:0071285 IDA cellular response to lithium ion
GO:0090398 IMP cellular senescence
GO:2000045 IEA regulation of G1/S transition of mitotic cell cycle
GO:2000178 IMP negative regulation of neural precursor cell proliferation

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000029544 id2b inhibitor of DNA binding 2, dominant negative helix-loop-helix protein, b protein_coding Danio_rerio
ENSDARG00000055283 id2a inhibitor of DNA binding 2, dominant negative helix-loop-helix protein, a protein_coding Danio_rerio
ENSG00000115738 ID2 inhibitor of DNA binding 2, dominant negative helix-loop-helix protein protein_coding Homo_sapiens

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