C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: nuclear receptor coactivator 1
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSMUSG00000020647 Ncoa1 10090 - 12:4247363-4477182 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENSMUST00000085814 Ncoa1-201 4247363-4477182 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENSMUST00000085814
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENSMUST00000085814 7.960±1.25 5.796±1.73 5.144±0.64 10.365±4.55 5.997±1.87 6.288±1.93 2.431±0.32 6.035±1.15 1.810±1.07 8.044±2.16 3.894±0.35 7.033±1.91 0.890±0.36 2.765±0.91

Conserved Regions

Gene is not located within a conserved region.

Gene Ontology
GO IDEvidence TypeGO Description
GO:0000435 IMP positive regulation of transcription from RNA polymerase II promoter by galactose
GO:0000790 IEA nuclear chromatin
GO:0001012 IEA RNA polymerase II regulatory region DNA binding
GO:0003677 IDA DNA binding
GO:0003682 IDA chromatin binding
GO:0003713 IDA transcription coactivator activity
GO:0004402 IEA histone acetyltransferase activity
GO:0004871 IEA signal transducer activity
GO:0005515 IPI protein binding
GO:0005654 TAS nucleoplasm
GO:0005737 IEA cytoplasm
GO:0006351 IEA transcription, DNA-templated
GO:0007165 IEA signal transduction
GO:0007595 IEA lactation
GO:0008134 IPI transcription factor binding
GO:0008584 IEA male gonad development
GO:0009725 IEA response to hormone
GO:0016922 IEA ligand-dependent nuclear receptor binding
GO:0019899 IEA enzyme binding
GO:0021549 IEA cerebellum development
GO:0021766 IEA hippocampus development
GO:0021854 IEA hypothalamus development
GO:0021987 IEA cerebral cortex development
GO:0030331 IEA estrogen receptor binding
GO:0030374 IEA ligand-dependent nuclear receptor transcription coactivator activity
GO:0032355 IEA response to estradiol
GO:0032403 IEA protein complex binding
GO:0032526 IEA response to retinoic acid
GO:0032570 IEA response to progesterone
GO:0032870 IEA cellular response to hormone stimulus
GO:0033142 IEA progesterone receptor binding
GO:0042698 IEA ovulation cycle
GO:0042974 IEA retinoic acid receptor binding
GO:0043005 IEA neuron projection
GO:0043065 IMP positive regulation of apoptotic process
GO:0043967 IMP histone H4 acetylation
GO:0045666 IMP positive regulation of neuron differentiation
GO:0045893 ISS positive regulation of transcription, DNA-templated
GO:0045925 IEA positive regulation of female receptivity
GO:0045944 IDA positive regulation of transcription from RNA polymerase II promoter
GO:0046965 IEA retinoid X receptor binding
GO:0046983 IEA protein dimerization activity
GO:0047485 IEA protein N-terminus binding
GO:0060179 IEA male mating behavior
GO:0060206 IEA estrous cycle phase
GO:0060713 IGI labyrinthine layer morphogenesis
GO:2001038 IMP regulation of cellular response to drug
GO:2001141 IMP regulation of RNA biosynthetic process

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000018257 ncoa1 nuclear receptor coactivator 1 protein_coding Danio_rerio
ENSG00000084676 NCOA1 nuclear receptor coactivator 1 protein_coding Homo_sapiens

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