C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: nuclear receptor coactivator 1
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000084676 NCOA1 9606 + 2:24491914-24770702 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000288599 NCOA1-201 24584477-24770702 protein_coding
  ENST00000348332 NCOA1-202 24584477-24770702 protein_coding
  ENST00000395856 NCOA1-003 24584541-24770702 protein_coding
  ENST00000405141 NCOA1-002 24492058-24770702 protein_coding
  ENST00000406961 NCOA1-001 24491932-24770702 protein_coding
  ENST00000407230 NCOA1-009 24564310-24768543 protein_coding
  ENST00000469850 NCOA1-004 24492023-24584484 processed_transcript
  ENST00000483904 NCOA1-008 24584476-24659129 retained_intron
  ENST00000486198 NCOA1-010 24707727-24711483 retained_intron
  ENST00000493773 NCOA1-011 24767771-24768388 retained_intron
  ENST00000496333 NCOA1-007 24491914-24644055 processed_transcript

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENST00000288599ENST00000348332ENST00000395856ENST00000406961ENST00000407230
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENST00000288599 2.894±0.00 3.472±0.00 N/A 5.889±1.95 3.784±0.00 N/A 2.272±0.00 4.209±0.00 2.369±1.03 2.656±0.81 7.977±0.00 3.085±1.97 3.154±0.62 5.057±0.00
ENST00000348332 N/A N/A N/A N/A N/A 1.485±0.00 0.511±0.00 N/A N/A N/A 1.810±0.00 0.928±0.00 2.231±0.00 2.020±0.00
ENST00000395856 1.833±0.00 3.811±0.00 2.114±0.00 4.599±0.00 1.333±0.00 2.737±0.00 3.046±0.00 N/A 1.204±0.00 3.459±0.00 N/A 1.263±0.66 N/A 5.038±0.11
ENST00000406961 N/A N/A N/A 2.780±0.00 N/A 2.194±0.00 N/A 2.207±0.00 N/A N/A N/A 5.955±0.00 2.036±0.00 2.003±0.00
ENST00000407230 N/A N/A 4.200±0.00 N/A N/A 2.277±0.00 2.590±0.05 N/A 3.562±0.00 N/A 2.912±0.00 0.803±0.00 N/A N/A

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_000025 CIL_000025_0002 CGP 2:24491914-24793382

Gene Ontology
GO IDEvidence TypeGO Description
GO:0000435 IDA positive regulation of transcription from RNA polymerase II promoter by galactose
GO:0000790 IDA nuclear chromatin
GO:0001012 IEA RNA polymerase II regulatory region DNA binding
GO:0001105 NAS RNA polymerase II transcription coactivator activity
GO:0003677 IEA DNA binding
GO:0003682 IEA chromatin binding
GO:0003713 IDA:IEA transcription coactivator activity
GO:0004402 IEA histone acetyltransferase activity
GO:0004871 IEA signal transducer activity
GO:0005515 IPI protein binding
GO:0005634 IEA nucleus
GO:0005654 TAS nucleoplasm
GO:0005737 IEA cytoplasm
GO:0006351 IDA transcription, DNA-templated
GO:0006355 IEA regulation of transcription, DNA-templated
GO:0007165 IEA signal transduction
GO:0007595 IEA lactation
GO:0008134 IEA transcription factor binding
GO:0008584 IEA male gonad development
GO:0009725 IEA response to hormone
GO:0016573 IEA histone acetylation
GO:0016922 IPI ligand-dependent nuclear receptor binding
GO:0019899 IPI enzyme binding
GO:0021549 IEA cerebellum development
GO:0021766 IEA hippocampus development
GO:0021854 IEA hypothalamus development
GO:0021987 IEA cerebral cortex development
GO:0030331 IEA estrogen receptor binding
GO:0030374 IEA:IDA ligand-dependent nuclear receptor transcription coactivator activity
GO:0030521 NAS androgen receptor signaling pathway
GO:0032355 IEA response to estradiol
GO:0032403 IEA protein complex binding
GO:0032526 IEA response to retinoic acid
GO:0032570 IEA response to progesterone
GO:0032870 IEA cellular response to hormone stimulus
GO:0033142 IEA progesterone receptor binding
GO:0035257 IEA:IDA nuclear hormone receptor binding
GO:0042698 IEA ovulation cycle
GO:0042974 IEA retinoic acid receptor binding
GO:0043005 IEA neuron projection
GO:0043065 IEA positive regulation of apoptotic process
GO:0043967 IEA histone H4 acetylation
GO:0044255 TAS cellular lipid metabolic process
GO:0044281 TAS small molecule metabolic process
GO:0045666 IEA positive regulation of neuron differentiation
GO:0045893 IDA positive regulation of transcription, DNA-templated
GO:0045925 IEA positive regulation of female receptivity
GO:0045944 NAS positive regulation of transcription from RNA polymerase II promoter
GO:0046965 IEA retinoid X receptor binding
GO:0046983 IEA protein dimerization activity
GO:0047485 IPI protein N-terminus binding
GO:0050681 NAS androgen receptor binding
GO:0060179 IEA male mating behavior
GO:0060206 IEA estrous cycle phase
GO:0060713 IEA labyrinthine layer morphogenesis
GO:2001038 IEA regulation of cellular response to drug
GO:2001141 IEA regulation of RNA biosynthetic process

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000018257 ncoa1 nuclear receptor coactivator 1 protein_coding Danio_rerio
ENSMUSG00000020647 Ncoa1 nuclear receptor coactivator 1 protein_coding Mus_musculus

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