C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: angiotensin I converting enzyme (peptidyl-dipeptidase A) 1
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSMUSG00000020681 Ace 10090 + 11:105967945-105989964 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENSMUST00000001963 Ace-001 105967945-105989964 protein_coding
  ENSMUST00000001964 Ace-003 105975208-105989253 protein_coding
  ENSMUST00000132280 Ace-002 105971323-105989260 protein_coding
  ENSMUST00000151657 Ace-004 105976605-105985113 processed_transcript

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENSMUST00000001963ENSMUST00000001964ENSMUST00000132280ENSMUST00000151657
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENSMUST00000001963 10.964±5.53 2.536±0.43 4.154±0.10 2.657±1.42 26.216±2.03 11.725±0.50 9.981±2.77 30.925±10.27 0.082±0.06 241.365±20.20 5.858±1.05 6.951±1.80 5.043±5.69 N/A
ENSMUST00000001964 N/A 1.662±0.00 N/A N/A N/A N/A N/A N/A 0.047±0.03 N/A N/A N/A 0.276±0.00 116.556±40.55
ENSMUST00000132280 3.923±2.50 1.192±0.38 1.276±0.11 0.947±0.25 13.831±4.06 6.139±0.46 3.936±1.17 9.245±2.86 0.068±0.03 94.221±22.23 2.025±0.54 3.940±1.56 2.103±2.24 21.619±1.02
ENSMUST00000151657 N/A N/A N/A N/A N/A N/A N/A N/A 0.100±0.00 N/A N/A N/A 1.085±0.00 N/A

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0009B9 CIL_0009B9_0002 VISTA 11:105834084-106435839
CIL_0006ZU CIL_0006ZU_0002 CGP 11:105933702-105989964

Gene Ontology
GO IDEvidence TypeGO Description
GO:0001822 IMP kidney development
GO:0002446 IMP neutrophil mediated immunity
GO:0003084 IMP positive regulation of systemic arterial blood pressure
GO:0004180 IEA carboxypeptidase activity
GO:0005515 IPI protein binding
GO:0005576 IEA extracellular region
GO:0005737 IDA cytoplasm
GO:0005886 IDA plasma membrane
GO:0006508 IEA proteolysis
GO:0007283 IMP spermatogenesis
GO:0008217 IDA regulation of blood pressure
GO:0008233 IMP peptidase activity
GO:0008237 IDA metallopeptidase activity
GO:0008241 IDA peptidyl-dipeptidase activity
GO:0016021 IEA integral component of membrane
GO:0042447 IDA hormone catabolic process
GO:0046872 IEA metal ion binding
GO:0060047 IMP heart contraction

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000079166 ace angiotensin I converting enzyme (peptidyl-dipeptidase A) 1 protein_coding Danio_rerio
ENSG00000159640 ACE angiotensin I converting enzyme protein_coding Homo_sapiens
ENSG00000264813 ACE Uncharacterized protein {ECO:0000313|Ensembl:ENSP00000464149} protein_coding Homo_sapiens

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