C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Transcript Info
Description: angiotensin I converting enzyme (peptidyl-dipeptidase A) 1
Transcript Accession Transcript Name Contained in Gene Tax ID Strand Position Biotype
ENSMUST00000001963 Ace-001 ENSMUSG00000020681 10090 + 11:105967945-105989964 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaENSMUST00000001963
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta
ENSMUST00000001963 10.964±5.53 2.536±0.43 4.154±0.10 2.657±1.42 26.216±2.03 11.725±0.50 9.981±2.77 30.925±10.27 0.082±0.06 241.365±20.20 5.858±1.05 6.951±1.80 5.043±5.69

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0009B9 CIL_0009B9_0002 VISTA 11:105834084-106435839
CIL_0006ZU CIL_0006ZU_0002 CGP 11:105933702-105989964

Gene Ontology

GO IDEvidence TypeGO Description
GO:0001822 IMP kidney development
GO:0002446 IMP neutrophil mediated immunity
GO:0003084 IMP positive regulation of systemic arterial blood pressure
GO:0004180 IEA carboxypeptidase activity
GO:0005515 IPI protein binding
GO:0005576 IEA extracellular region
GO:0005737 IDA cytoplasm
GO:0005886 IDA plasma membrane
GO:0006508 IEA proteolysis
GO:0007283 IMP spermatogenesis
GO:0008217 IDA regulation of blood pressure
GO:0008233 IMP peptidase activity
GO:0008237 IDA metallopeptidase activity
GO:0008241 IDA peptidyl-dipeptidase activity
GO:0016021 IEA integral component of membrane
GO:0042447 IDA hormone catabolic process
GO:0046872 IEA metal ion binding
GO:0060047 IMP heart contraction

Homologs

ENSEMBL Accession Gene Name Biotype Species E-Value Bit Score
ENST00000290863 ACE-007 protein_coding Homo_sapiens 0 1855
ENST00000290866 ACE-001 protein_coding Homo_sapiens 0 3847
ENST00000413513 ACE-009 protein_coding Homo_sapiens 0 1334
ENST00000421982 ACE-201 protein_coding Homo_sapiens 0 1640
ENST00000428043 ACE-201 protein_coding Homo_sapiens 0 3635
ENST00000577418 ACE-018 processed_transcript Homo_sapiens 0 669
ENST00000577647 ACE-001 nonsense_mediated_decay Homo_sapiens 0 1640
ENST00000578679 ACE-019 retained_intron Homo_sapiens 0 339
ENST00000578839 ACE-008 nonsense_mediated_decay Homo_sapiens 0 859
ENST00000579314 ACE-006 nonsense_mediated_decay Homo_sapiens 0 1642
ENST00000579409 ACE-020 protein_coding Homo_sapiens 0 379
ENST00000580318 ACE-012 nonsense_mediated_decay Homo_sapiens 0 508
ENST00000582244 ACE-021 retained_intron Homo_sapiens 0 315
ENST00000582627 ACE-011 protein_coding Homo_sapiens 0 769
ENST00000582678 ACE-003 nonsense_mediated_decay Homo_sapiens 0 1650
ENST00000582761 ACE-017 protein_coding Homo_sapiens 0 545
ENST00000583645 ACE-022 retained_intron Homo_sapiens 0 326
ENST00000584529 ACE-004 processed_transcript Homo_sapiens 0 1358
ENST00000584865 ACE-016 retained_intron Homo_sapiens 0 806

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