C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: ArfGAP with dual PH domains 2
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSMUSG00000020709 Adap2 10090 + 11:80154105-80178958 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENSMUST00000021050 Adap2-001 80154105-80178958 protein_coding
  ENSMUST00000134118 Adap2-002 80154116-80165776 nonsense_mediated_decay

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENSMUST00000021050ENSMUST00000134118
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENSMUST00000021050 6.462±1.62 3.475±0.40 2.743±0.30 0.642±0.22 1.829±0.28 1.556±0.37 1.789±0.54 10.589±1.54 4.710±2.33 4.251±2.27 0.776±0.20 2.459±1.25 8.457±4.14 0.122±0.07
ENSMUST00000134118 N/A 9.802±3.21 N/A 1.539±0.00 6.315±0.49 N/A N/A N/A 9.514±2.27 7.117±0.00 N/A 5.185±1.52 N/A 0.267±0.17

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_000740 CIL_000740_0002 CGP 11:80136678-80178958
CIL_00073Y CIL_00073Y_0002 CGP 11:80154105-80199757

Gene Ontology
GO IDEvidence TypeGO Description
GO:0005515 IEA protein binding
GO:0005546 ISS phosphatidylinositol-4,5-bisphosphate binding
GO:0005547 ISS phosphatidylinositol-3,4,5-trisphosphate binding
GO:0005737 ISS cytoplasm
GO:0005740 ISS mitochondrial envelope
GO:0005886 ISS plasma membrane
GO:0007507 NAS heart development
GO:0008060 IEA ARF GTPase activator activity
GO:0008270 IEA zinc ion binding
GO:0032312 IEA regulation of ARF GTPase activity
GO:0043325 ISS phosphatidylinositol-3,4-bisphosphate binding
GO:0043533 ISS inositol 1,3,4,5 tetrakisphosphate binding
GO:0043547 IEA positive regulation of GTPase activity

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000070565 ADAP2 ArfGAP with dual PH domains 2 protein_coding Danio_rerio
ENSG00000184060 ADAP2 ArfGAP with dual PH domains 2 protein_coding Homo_sapiens

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