C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: platelet-activating factor acetylhydrolase, isoform 1b, subunit 1
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSMUSG00000020745 Pafah1b1 10090 - 11:74673949-74724670 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENSMUST00000021091 Pafah1b1-002 74673949-74724670 protein_coding
  ENSMUST00000102520 Pafah1b1-004 74673950-74723858 protein_coding
  ENSMUST00000126341 Pafah1b1-005 74673949-74724335 retained_intron
  ENSMUST00000155493 Pafah1b1-001 74689085-74723171 protein_coding
  ENSMUST00000156794 Pafah1b1-006 74673950-74724318 retained_intron

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENSMUST00000021091ENSMUST00000102520ENSMUST00000126341ENSMUST00000155493ENSMUST00000156794
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENSMUST00000021091 3.355±0.61 4.565±0.68 14.913±6.75 23.252±12.36 4.813±0.76 8.155±1.28 3.774±0.06 3.955±1.47 6.033±2.76 8.729±3.42 10.500±2.04 8.588±1.98 15.526±6.13 9.666±6.44
ENSMUST00000102520 4.324±0.88 6.178±1.86 4.648±0.00 7.834±0.00 8.223±2.40 4.603±0.88 N/A 4.203±2.64 3.706±0.45 7.256±0.92 N/A 5.038±1.62 10.531±4.22 8.417±4.25
ENSMUST00000126341 N/A N/A N/A N/A N/A N/A N/A N/A 1.470±0.20 N/A N/A N/A N/A N/A
ENSMUST00000155493 N/A N/A N/A 407.510±0.00 N/A N/A N/A N/A N/A N/A N/A 250.204±0.00 451.565±97.09 446.074±0.00
ENSMUST00000156794 N/A N/A N/A N/A N/A N/A N/A N/A 2.520±0.55 N/A N/A 1.769±0.00 N/A N/A

Conserved Regions

Gene is not located within a conserved region.

Gene Ontology
GO IDEvidence TypeGO Description
GO:0000132 IEA establishment of mitotic spindle orientation
GO:0000226 IGI microtubule cytoskeleton organization
GO:0000235 IEA astral microtubule
GO:0000776 IEA kinetochore
GO:0001667 IMP ameboidal cell migration
GO:0001675 IMP acrosome assembly
GO:0001764 IGI neuron migration
GO:0001961 IMP positive regulation of cytokine-mediated signaling pathway
GO:0005515 IPI protein binding
GO:0005635 ISS nuclear envelope
GO:0005737 IDA cytoplasm
GO:0005813 IDA centrosome
GO:0005829 IEA cytosol
GO:0005871 IEA kinesin complex
GO:0005875 IDA microtubule associated complex
GO:0005938 IEA cell cortex
GO:0007017 IEA microtubule-based process
GO:0007067 IEA mitotic nuclear division
GO:0007097 IEA nuclear migration
GO:0007268 IMP synaptic transmission
GO:0007405 IMP neuroblast proliferation
GO:0007420 IEA brain development
GO:0007611 IMP learning or memory
GO:0008017 IDA microtubule binding
GO:0008090 IDA retrograde axon cargo transport
GO:0008344 IMP adult locomotory behavior
GO:0009306 IMP protein secretion
GO:0010977 IEA negative regulation of neuron projection development
GO:0015630 IDA microtubule cytoskeleton
GO:0016020 IEA membrane
GO:0016042 IEA lipid catabolic process
GO:0016477 IMP cell migration
GO:0017145 IEA stem cell division
GO:0019226 IMP transmission of nerve impulse
GO:0021540 IEA corpus callosum morphogenesis
GO:0021766 IMP hippocampus development
GO:0021819 IGI layer formation in cerebral cortex
GO:0021895 IEA cerebral cortex neuron differentiation
GO:0021987 IMP cerebral cortex development
GO:0030036 IMP actin cytoskeleton organization
GO:0030424 IEA axon
GO:0030426 IEA growth cone
GO:0031023 IEA microtubule organizing center organization
GO:0031252 IDA cell leading edge
GO:0031512 IDA motile primary cilium
GO:0031982 IEA vesicle
GO:0032319 IMP regulation of Rho GTPase activity
GO:0032403 IEA protein complex binding
GO:0036035 IMP osteoclast development
GO:0042803 IPI protein homodimerization activity
GO:0043005 IEA neuron projection
GO:0043025 IEA neuronal cell body
GO:0045502 IEA dynein binding
GO:0045505 IEA dynein intermediate chain binding
GO:0045773 IEA positive regulation of axon extension
GO:0045931 IEA positive regulation of mitotic cell cycle
GO:0046329 IGI negative regulation of JNK cascade
GO:0047496 IGI vesicle transport along microtubule
GO:0048471 IDA perinuclear region of cytoplasm
GO:0048854 IEA brain morphogenesis
GO:0050885 IMP neuromuscular process controlling balance
GO:0051081 IMP nuclear envelope disassembly
GO:0051219 IPI phosphoprotein binding
GO:0051660 IEA establishment of centrosome localization
GO:0070062 IEA extracellular vesicular exosome

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000026595 pafah1b1b platelet-activating factor acetylhydrolase, isoform Ib, alpha subunit b protein_coding Danio_rerio
ENSDARG00000032013 pafah1b1a platelet-activating factor acetylhydrolase, isoform Ib, alpha subunit a protein_coding Danio_rerio
ENSG00000007168 PAFAH1B1 platelet-activating factor acetylhydrolase 1b, regulatory subunit 1 (45kDa) protein_coding Homo_sapiens

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