C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, epsilon polypeptide
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSMUSG00000020849 Ywhae 10090 + 11:75732869-75765845 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENSMUST00000067664 Ywhae-001 75732869-75765845 protein_coding
  ENSMUST00000131398 Ywhae-005 75733148-75756872 protein_coding
  ENSMUST00000134745 Ywhae-002 75732913-75764623 nonsense_mediated_decay
  ENSMUST00000153038 Ywhae-003 75732961-75757116 retained_intron
  ENSMUST00000155057 Ywhae-004 75751604-75759315 retained_intron

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENSMUST00000067664ENSMUST00000134745
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENSMUST00000067664 121.493±5.90 79.569±8.80 113.069±40.52 315.584±152.39 98.014±2.40 79.352±6.60 108.638±18.50 153.577±13.12 106.877±44.24 125.441±17.21 106.856±13.03 102.649±17.88 168.988±88.95 105.337±44.63
ENSMUST00000134745 N/A N/A N/A 891.495±0.00 N/A 76.015±29.51 N/A N/A 43.484±0.00 81.228±17.94 N/A 258.789±338.68 1123.978±588.27 1164.370±0.00

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_000034 CIL_000034_0002 CGP 11:75679259-75765845

Gene Ontology
GO IDEvidence TypeGO Description
GO:0001764 IGI neuron migration
GO:0005515 IPI protein binding
GO:0005739 IDA mitochondrion
GO:0005829 TAS cytosol
GO:0005871 IEA kinesin complex
GO:0005925 IEA focal adhesion
GO:0006605 IDA protein targeting
GO:0015459 IEA potassium channel regulator activity
GO:0016020 IEA membrane
GO:0019899 IEA enzyme binding
GO:0019904 IDA protein domain specific binding
GO:0021762 IEA substantia nigra development
GO:0021766 IMP hippocampus development
GO:0021987 IMP cerebral cortex development
GO:0023026 IEA MHC class II protein complex binding
GO:0030424 IEA axon
GO:0030659 TAS cytoplasmic vesicle membrane
GO:0032403 IEA protein complex binding
GO:0035308 IDA negative regulation of protein dephosphorylation
GO:0042826 IEA histone deacetylase binding
GO:0044325 IEA ion channel binding
GO:0044822 IEA poly(A) RNA binding
GO:0046982 IEA protein heterodimerization activity
GO:0050815 IEA phosphoserine binding
GO:0051219 IEA phosphoprotein binding
GO:0060306 IEA regulation of membrane repolarization
GO:0070062 IEA extracellular vesicular exosome
GO:1901016 IEA regulation of potassium ion transmembrane transporter activity
GO:1902309 IEA negative regulation of peptidyl-serine dephosphorylation

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000006399 ywhae1 tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, epsilon polypeptide 1 protein_coding Danio_rerio
ENSDARG00000017014 ywhae2 tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, epsilon polypeptide 2 protein_coding Danio_rerio
ENSG00000108953 YWHAE tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, epsilon protein_coding Homo_sapiens

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