C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: ATP citrate lyase
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSMUSG00000020917 Acly 10090 - 11:100476353-100528000 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENSMUST00000007131 Acly-001 100476356-100528000 protein_coding
  ENSMUST00000107385 Acly-006 100500579-100527869 protein_coding
  ENSMUST00000107389 Acly-005 100476353-100528000 protein_coding
  ENSMUST00000152969 Acly-003 100482259-100494199 processed_transcript
  ENSMUST00000154151 Acly-002 100477226-100479511 processed_transcript
  ENSMUST00000154888 Acly-004 100498248-100499098 processed_transcript
  ENSMUST00000165111 Acly-201 100476358-100523598 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENSMUST00000007131ENSMUST00000107385ENSMUST00000107389ENSMUST00000154151ENSMUST00000165111
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENSMUST00000007131 321.573±46.68 279.867±17.88 22.631±3.95 27.891±15.05 306.539±41.52 43.976±4.18 17.152±5.30 59.750±3.71 42.258±13.45 65.169±3.63 0.952±0.24 58.948±17.01 19.336±12.93 7.944±0.66
ENSMUST00000107385 136.937±0.00 112.466±0.00 N/A N/A N/A 24.189±0.00 N/A N/A N/A N/A N/A 42.403±6.55 N/A 1.737±0.00
ENSMUST00000107389 104.687±3.33 89.406±12.21 13.563±2.60 21.551±10.59 94.275±9.81 28.290±3.57 8.138±1.36 16.948±2.35 14.119±3.16 29.413±1.80 1.027±0.33 26.268±6.27 17.660±9.14 4.474±1.84
ENSMUST00000154151 N/A N/A N/A 43.647±0.00 N/A N/A N/A N/A N/A N/A N/A N/A 62.186±28.28 9.514±0.00
ENSMUST00000165111 N/A N/A N/A 13.507±0.00 N/A N/A N/A N/A N/A N/A 1.450±0.22 68.623±23.63 21.300±9.82 2.300±0.00

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0000KS CIL_0000KS_0003 CGP 11:100462614-100528000
CIL_0006EG CIL_0006EG_0002 CGP 11:100476353-100572568

Gene Ontology
GO IDEvidence TypeGO Description
GO:0003878 TAS ATP citrate synthase activity
GO:0004775 IEA succinate-CoA ligase (ADP-forming) activity
GO:0005515 IPI protein binding
GO:0005524 IEA ATP binding
GO:0005622 TAS intracellular
GO:0005634 IEA nucleus
GO:0005739 IDA mitochondrion
GO:0005886 IEA plasma membrane
GO:0006085 TAS acetyl-CoA biosynthetic process
GO:0008610 ISS lipid biosynthetic process
GO:0016020 IEA membrane
GO:0044262 IEA cellular carbohydrate metabolic process
GO:0046872 IEA metal ion binding
GO:0048037 IEA cofactor binding
GO:0070062 IEA extracellular vesicular exosome

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000017738 aclya ATP citrate lyase a protein_coding Danio_rerio
ENSDARG00000055652 aclyb ATP citrate lyase b protein_coding Danio_rerio
ENSG00000131473 ACLY ATP citrate lyase protein_coding Homo_sapiens

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