C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: ataxin 3
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSMUSG00000021189 Atxn3 10090 - 12:101918901-101958246 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENSMUST00000021606 Atxn3-001 101918901-101958246 protein_coding
  ENSMUST00000159883 Atxn3-004 101932949-101958148 protein_coding
  ENSMUST00000160186 Atxn3-005 101923081-101934355 nonsense_mediated_decay
  ENSMUST00000160251 Atxn3-003 101932924-101958243 protein_coding
  ENSMUST00000161011 Atxn3-002 101932926-101958243 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENSMUST00000021606ENSMUST00000159883ENSMUST00000160186ENSMUST00000161011
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENSMUST00000021606 3.740±0.93 0.594±0.18 6.261±0.45 3.205±0.75 2.470±1.16 1.955±0.64 1.405±0.13 2.767±1.01 3.865±1.55 4.537±1.00 0.832±0.33 1.863±1.65 2.760±0.77 4.159±1.43
ENSMUST00000159883 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A 36.866±0.00
ENSMUST00000160186 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A 7.326±0.00 72.332±0.00
ENSMUST00000161011 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A 0.877±0.00 N/A N/A 88.172±25.94

Conserved Regions

Gene is not located within a conserved region.

Gene Ontology
GO IDEvidence TypeGO Description
GO:0000226 ISS microtubule cytoskeleton organization
GO:0001012 IEA RNA polymerase II regulatory region DNA binding
GO:0004221 IDA ubiquitin thiolesterase activity
GO:0004407 IEA histone deacetylase activity
GO:0004843 IDA ubiquitin-specific protease activity
GO:0005515 IPI protein binding
GO:0005634 IDA nucleus
GO:0005737 IDA cytoplasm
GO:0005759 IDA mitochondrial matrix
GO:0005829 ISS cytosol
GO:0006351 IEA transcription, DNA-templated
GO:0006355 IEA regulation of transcription, DNA-templated
GO:0006511 IMP ubiquitin-dependent protein catabolic process
GO:0006515 IMP misfolded or incompletely synthesized protein catabolic process
GO:0008242 IEA omega peptidase activity
GO:0010810 IMP:ISS regulation of cell-substrate adhesion
GO:0016579 IEA protein deubiquitination
GO:0030036 ISS actin cytoskeleton organization
GO:0031625 IPI ubiquitin protein ligase binding
GO:0031966 IDA mitochondrial membrane
GO:0034605 IMP cellular response to heat
GO:0035520 IDA monoubiquitinated protein deubiquitination
GO:0035640 IMP exploration behavior
GO:0042405 IDA nuclear inclusion body
GO:0042802 ISS identical protein binding
GO:0043161 IMP proteasome-mediated ubiquitin-dependent protein catabolic process
GO:0045104 ISS intermediate filament cytoskeleton organization
GO:0051117 ISS ATPase binding
GO:0061578 ISS Lys63-specific deubiquitinase activity
GO:0070536 ISS protein K63-linked deubiquitination
GO:0070932 IEA histone H3 deacetylation
GO:0071108 ISS protein K48-linked deubiquitination
GO:0071218 IMP cellular response to misfolded protein
GO:1990380 ISS Lys48-specific deubiquitinase activity

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000009264 ATXN3 ataxin 3 protein_coding Danio_rerio
ENSG00000123594 ATXN3L ataxin 3-like protein_coding Homo_sapiens

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