C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: X-ray repair complementing defective repair in Chinese hamster cells 3
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSMUSG00000021287 Xrcc3 10090 - 12:111803192-111813873 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENSMUST00000021715 Xrcc3-001 111803193-111813841 protein_coding
  ENSMUST00000124064 Xrcc3-008 111804913-111812201 processed_transcript
  ENSMUST00000127281 Xrcc3-002 111803192-111812201 nonsense_mediated_decay
  ENSMUST00000129258 Xrcc3-004 111809901-111813852 processed_transcript
  ENSMUST00000132177 Xrcc3-006 111809766-111812221 processed_transcript
  ENSMUST00000133679 Xrcc3-005 111811504-111812221 processed_transcript
  ENSMUST00000145109 Xrcc3-003 111805074-111813873 processed_transcript
  ENSMUST00000146491 Xrcc3-007 111804979-111809982 retained_intron

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBreastLiverOvaryPlacentaTestisENSMUST00000021715
Transcript ID Adipose Adrenal Breast Liver Ovary Placenta Testis
ENSMUST00000021715 7.730±2.57 9.820±2.40 5.578±1.54 8.990±6.32 8.018±2.60 6.058±0.11 3.795±0.43

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_00079L CIL_00079L_0002 CGP 12:111713261-111807844
CIL_00020Z CIL_00020Z_0002 CGP 12:111803192-111828388

Gene Ontology
GO IDEvidence TypeGO Description
GO:0000400 IEA four-way junction DNA binding
GO:0000724 ISS double-strand break repair via homologous recombination
GO:0000737 IEA DNA catabolic process, endonucleolytic
GO:0003677 IEA DNA binding
GO:0005515 IEA protein binding
GO:0005524 IEA ATP binding
GO:0005634 ISS nucleus
GO:0005657 ISS replication fork
GO:0005737 ISS cytoplasm
GO:0005739 IEA mitochondrion
GO:0006200 IEA ATP catabolic process
GO:0006259 IEA DNA metabolic process
GO:0006281 IEA DNA repair
GO:0008094 IEA DNA-dependent ATPase activity
GO:0008821 IEA crossover junction endodeoxyribonuclease activity
GO:0010033 IEA response to organic substance
GO:0010824 ISS regulation of centrosome duplication
GO:0033065 ISS Rad51C-XRCC3 complex
GO:0048471 ISS perinuclear region of cytoplasm
GO:0071140 ISS resolution of mitotic recombination intermediates
GO:0090267 ISS positive regulation of mitotic cell cycle spindle assembly checkpoint

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000017928 xrcc3 X-ray repair complementing defective repair in Chinese hamster cells 3 protein_coding Danio_rerio
ENSG00000126215 XRCC3 X-ray repair complementing defective repair in Chinese hamster cells 3 protein_coding Homo_sapiens

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