C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: coagulation factor XII (Hageman factor)
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSMUSG00000021492 F12 10090 - 13:55417958-55426793 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENSMUST00000021948 F12-001 55417958-55426793 protein_coding
  ENSMUST00000170921 F12-002 55418064-55426779 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaENSMUST00000021948ENSMUST00000170921
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta
ENSMUST00000021948 0.062±0.01 0.155±0.10 0.036±0.00 0.080±0.04 0.710±0.52 0.062±0.03 0.052±0.01 0.028±0.02 199.926±110.62 0.105±0.05 0.034±0.00 0.185±0.14 0.128±0.10
ENSMUST00000170921 0.045±0.00 N/A N/A 0.239±0.18 N/A 0.142±0.07 0.158±0.00 0.278±0.00 N/A 0.066±0.00 N/A 0.491±0.26 N/A

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0008A2 CIL_0008A2_0002 VISTA 13:55104361-55707564
CIL_0002YG CIL_0002YG_0002 CGP 13:55414753-55426793
CIL_0002YH CIL_0002YH_0002 CGP 13:55417958-55460925

Gene Ontology
GO IDEvidence TypeGO Description
GO:0002353 IEA plasma kallikrein-kinin cascade
GO:0002542 IEA Factor XII activation
GO:0004252 IEA serine-type endopeptidase activity
GO:0005615 IMP extracellular space
GO:0006508 IEA proteolysis
GO:0007596 IMP blood coagulation
GO:0008233 IMP peptidase activity
GO:0010756 IEA positive regulation of plasminogen activation
GO:0016485 IEA protein processing
GO:0016540 IEA protein autoprocessing
GO:0030193 IMP regulation of blood coagulation
GO:0030194 IEA positive regulation of blood coagulation
GO:0031638 IEA zymogen activation
GO:0042730 IEA fibrinolysis
GO:0051788 IEA response to misfolded protein
GO:0051919 IEA positive regulation of fibrinolysis
GO:0070009 IEA serine-type aminopeptidase activity
GO:0070062 IEA extracellular vesicular exosome

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSG00000131187 F12 coagulation factor XII (Hageman factor) protein_coding Homo_sapiens

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