| Transcript ID | Kidney | Liver |
|---|---|---|
| ENST00000253496 | 64.146±0.00 | 154.590±0.00 |
C-It-Loci: A knowledge database for tissue-enriched loci.
Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main
Gene Info | |||||
|---|---|---|---|---|---|
| Description: | coagulation factor XII (Hageman factor) | ||||
| Gene Accession | Gene Name | Tax ID | Strand | Position | Gene Biotype |
ENSG00000131187  |
F12 | 9606 | - |
5:177402140-177409576  |
protein_coding |
| Transcript Accession | Transcript Name | Position | Transcript Biotype | ||
| ENST00000253496 |
F12-001 | 177402140-177409576 | protein_coding | ||
| ENST00000502854 |
F12-002 | 177402160-177404472 | retained_intron | ||
| ENST00000503736 |
F12-004 | 177403492-177404981 | retained_intron | ||
| ENST00000504406 |
F12-005 | 177402163-177403750 | retained_intron | ||
| ENST00000510358 |
F12-003 | 177402172-177404472 | retained_intron | ||
| ENST00000514943 |
F12-006 | 177402625-177403526 | processed_transcript | ||
Expression Patterns
|
Conserved Regions | |||
|---|---|---|---|
| Region ID | Sub-Region | Region Type | Position |
| CIL_0008A2 | CIL_0008A2_0001 | VISTA | 5:177089375-177692188 |
| CIL_0002YG | CIL_0002YG_0001 | CGP | 5:177400107-177409576 |
| CIL_0002YH | CIL_0002YH_0001 | CGP | 5:177402140-177442901 |
Gene Ontology |
||
|---|---|---|
| GO ID | Evidence Type | GO Description |
| GO:0002353 | IDA | plasma kallikrein-kinin cascade |
| GO:0002542 | IDA | Factor XII activation |
| GO:0003824 | IEA | catalytic activity |
| GO:0004252 | IDA:IEA | serine-type endopeptidase activity |
| GO:0005509 | IEA | calcium ion binding |
| GO:0005515 | IPI:IEA | protein binding |
| GO:0005576 | TAS:IEA | extracellular region |
| GO:0005615 | IDA:IEA | extracellular space |
| GO:0005886 | TAS | plasma membrane |
| GO:0006508 | IEA | proteolysis |
| GO:0007596 | TAS | blood coagulation |
| GO:0007597 | IC | blood coagulation, intrinsic pathway |
| GO:0008233 | IEA | peptidase activity |
| GO:0010756 | IDA | positive regulation of plasminogen activation |
| GO:0016485 | IDA | protein processing |
| GO:0016540 | IDA | protein autoprocessing |
| GO:0030193 | IEA | regulation of blood coagulation |
| GO:0030194 | IDA | positive regulation of blood coagulation |
| GO:0031638 | IDA | zymogen activation |
| GO:0042730 | IEA | fibrinolysis |
| GO:0045087 | TAS | innate immune response |
| GO:0051787 | IC | misfolded protein binding |
| GO:0051788 | IDA | response to misfolded protein |
| GO:0051919 | IDA | positive regulation of fibrinolysis |
| GO:0070009 | IEA | serine-type aminopeptidase activity |
| GO:0070062 | IDA | extracellular vesicular exosome |
Homologs | |||||
| ENSEMBL Accession | Gene Name | Description | Biotype | Species | |
|
ENSMUSG00000021492
|
F12 | coagulation factor XII (Hageman factor) | protein_coding | Mus_musculus | |
