C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: adenylate cyclase 2
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSMUSG00000021536 Adcy2 10090 - 13:68620043-68999541 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENSMUST00000022013 Adcy2-201 68620043-68999541 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENSMUST00000022013
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENSMUST00000022013 1.035±0.63 0.325±0.10 1.644±0.06 12.851±10.52 2.040±1.71 0.848±0.14 0.198±0.05 0.350±0.11 0.256±0.23 6.390±1.58 9.152±0.85 1.737±0.75 0.283±0.16 1.039±0.63

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_000403 CIL_000403_0002 CGP 13:68597439-68999541
CIL_0001EG CIL_0001EG_0002 CGP 13:68620043-69533839

Gene Ontology
GO IDEvidence TypeGO Description
GO:0000166 IEA nucleotide binding
GO:0004016 TAS:ISS adenylate cyclase activity
GO:0005515 IEA protein binding
GO:0005524 IEA ATP binding
GO:0005622 IEA intracellular
GO:0005737 IEA cytoplasm
GO:0005886 TAS:IDA plasma membrane
GO:0006171 TAS:ISS cAMP biosynthetic process
GO:0007188 TAS adenylate cyclase-modulating G-protein coupled receptor signaling pathway
GO:0007190 TAS activation of adenylate cyclase activity
GO:0008179 IPI adenylate cyclase binding
GO:0008294 IEA calcium- and calmodulin-responsive adenylate cyclase activity
GO:0016020 IDA:ISS membrane
GO:0016021 IEA integral component of membrane
GO:0030425 IDA dendrite
GO:0031683 IEA G-protein beta/gamma-subunit complex binding
GO:0035556 IEA intracellular signal transduction
GO:0043234 IEA protein complex
GO:0045121 IEA membrane raft
GO:0046872 IEA metal ion binding
GO:0046982 IPI protein heterodimerization activity

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000014588 adcy2b adenylate cyclase 2b (brain) protein_coding Danio_rerio
ENSDARG00000058392 adcy2a adenylate cyclase 2a protein_coding Danio_rerio
ENSG00000078295 ADCY2 adenylate cyclase 2 (brain) protein_coding Homo_sapiens

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