C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: programmed cell death 6
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSMUSG00000021576 Pdcd6 10090 - 13:74303121-74317326 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENSMUST00000022060 Pdcd6-201 74303121-74317326 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENSMUST00000022060
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENSMUST00000022060 26.335±3.39 68.508±20.67 28.769±6.82 24.521±7.30 33.768±6.87 38.708±7.98 11.952±2.56 35.006±3.30 29.293±7.90 32.719±4.13 3.408±1.46 43.845±14.47 31.641±10.64 13.217±4.19

Conserved Regions

Gene is not located within a conserved region.

Gene Ontology
GO IDEvidence TypeGO Description
GO:0001525 IEA angiogenesis
GO:0001938 ISS positive regulation of endothelial cell proliferation
GO:0004198 IBA calcium-dependent cysteine-type endopeptidase activity
GO:0005509 IMP calcium ion binding
GO:0005515 IPI protein binding
GO:0005634 ISS nucleus
GO:0005737 IDA cytoplasm
GO:0005768 IEA endosome
GO:0005783 IEA endoplasmic reticulum
GO:0006508 IBA proteolysis
GO:0006886 ISS intracellular protein transport
GO:0006915 IDA apoptotic process
GO:0006919 IDA activation of cysteine-type endopeptidase activity involved in apoptotic process
GO:0010595 ISS positive regulation of endothelial cell migration
GO:0016020 IEA membrane
GO:0030948 ISS negative regulation of vascular endothelial growth factor receptor signaling pathway
GO:0031410 IEA cytoplasmic vesicle
GO:0032007 ISS negative regulation of TOR signaling
GO:0034605 ISS cellular response to heat
GO:0036324 ISS vascular endothelial growth factor receptor-2 signaling pathway
GO:0042803 IPI protein homodimerization activity
GO:0045766 ISS positive regulation of angiogenesis
GO:0046983 IPI protein dimerization activity
GO:0048306 IPI calcium-dependent protein binding
GO:0051592 IDA response to calcium ion
GO:0051898 ISS negative regulation of protein kinase B signaling
GO:0060090 ISS binding, bridging
GO:0070062 IEA extracellular vesicular exosome

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000005220 pdcd6 programmed cell death 6 protein_coding Danio_rerio
ENSG00000249915 PDCD6 programmed cell death 6 protein_coding Homo_sapiens

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