C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: telomerase reverse transcriptase
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSMUSG00000021611 Tert 10090 + 13:73627001-73649041 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENSMUST00000022104 Tert-201 73627001-73649041 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENSMUST00000022104
Transcript ID Adipose Adrenal Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENSMUST00000022104 1.142±0.69 3.993±0.52 1.487±1.03 0.703±0.28 0.568±0.26 0.059±0.03 0.288±0.04 1.685±1.20 0.529±0.18 0.020±0.01 2.717±1.45 0.875±0.49 0.247±0.17

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0000JR CIL_0000JR_0002 CGP 13:73627001-73678023

Gene Ontology
GO IDEvidence TypeGO Description
GO:0000781 IEA chromosome, telomeric region
GO:0003677 IEA DNA binding
GO:0003720 IDA telomerase activity
GO:0003721 IEA telomeric template RNA reverse transcriptase activity
GO:0005515 IPI protein binding
GO:0005634 IEA nucleus
GO:0005654 IEA nucleoplasm
GO:0005697 IEA telomerase holoenzyme complex
GO:0005737 IEA cytoplasm
GO:0007004 IEA telomere maintenance via telomerase
GO:0016605 IEA PML body
GO:0022616 IEA DNA strand elongation
GO:0032203 IEA telomere formation via telomerase
GO:0042803 IEA protein homodimerization activity
GO:0046872 IEA metal ion binding
GO:0070034 IEA telomeric RNA binding
GO:0090399 IEA replicative senescence
GO:2001240 IEA negative regulation of extrinsic apoptotic signaling pathway in absence of ligand

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000042637 tert telomerase reverse transcriptase protein_coding Danio_rerio
ENSG00000164362 TERT telomerase reverse transcriptase protein_coding Homo_sapiens

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