C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: polo-like kinase 2
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSMUSG00000021701 Plk2 10090 + 13:110395044-110400844 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENSMUST00000022212 Plk2-201 110395044-110400844 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENSMUST00000022212
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENSMUST00000022212 8.121±1.92 3.047±1.23 9.722±2.01 36.370±19.17 20.644±3.66 4.523±1.24 3.979±0.31 1.715±0.32 2.572±1.82 15.224±2.69 2.507±0.25 6.757±3.33 16.994±7.44 2.163±0.86

Conserved Regions

Gene is not located within a conserved region.

Gene Ontology
GO IDEvidence TypeGO Description
GO:0000082 ISS G1/S transition of mitotic cell cycle
GO:0000278 IMP mitotic cell cycle
GO:0004674 IDA protein serine/threonine kinase activity
GO:0004871 IEA signal transducer activity
GO:0005524 IEA ATP binding
GO:0005622 ISS intracellular
GO:0005813 ISS centrosome
GO:0005814 ISS centriole
GO:0006468 IDA protein phosphorylation
GO:0007052 ISS mitotic spindle organization
GO:0007093 IMP mitotic cell cycle checkpoint
GO:0007265 ISS Ras protein signal transduction
GO:0007613 IMP memory
GO:0030425 ISS dendrite
GO:0032092 IEA positive regulation of protein binding
GO:0032403 IEA protein complex binding
GO:0032436 IEA positive regulation of proteasomal ubiquitin-dependent protein catabolic process
GO:0032486 ISS Rap protein signal transduction
GO:0043066 IMP negative regulation of apoptotic process
GO:0043123 IEA positive regulation of I-kappaB kinase/NF-kappaB signaling
GO:0046599 ISS regulation of centriole replication
GO:0048167 IMP regulation of synaptic plasticity
GO:0060291 ISS long-term synaptic potentiation
GO:0060292 ISS long term synaptic depression
GO:0061000 IEA negative regulation of dendritic spine development

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000090752 plk2a polo-like kinase 2a (Drosophila) protein_coding Danio_rerio
ENSG00000145632 PLK2 polo-like kinase 2 protein_coding Homo_sapiens

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