C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: thrombospondin 4
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSMUSG00000021702 Thbs4 10090 - 13:92751590-92794818 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENSMUST00000022213 Thbs4-001 92751590-92794818 protein_coding
  ENSMUST00000168299 Thbs4-002 92773161-92774974 retained_intron

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENSMUST00000022213ENSMUST00000168299
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENSMUST00000022213 0.673±0.58 0.862±0.16 0.170±0.05 0.857±0.56 4.186±2.99 101.464±8.88 1.378±0.27 1.088±0.13 0.060±0.05 1.295±0.76 5.778±1.91 52.984±13.13 0.243±0.24 0.081±0.04
ENSMUST00000168299 0.178±0.00 N/A N/A N/A N/A N/A N/A 1.710±0.00 N/A N/A N/A N/A 0.246±0.00 N/A

Conserved Regions

Gene is not located within a conserved region.

Gene Ontology

GO IDEvidence TypeGO Description
GO:0001938 IEA positive regulation of endothelial cell proliferation
GO:0005178 IEA integrin binding
GO:0005509 IEA calcium ion binding
GO:0005515 IPI protein binding
GO:0005604 IEA basement membrane
GO:0005615 IDA extracellular space
GO:0005783 IDA endoplasmic reticulum
GO:0006986 IEA response to unfolded protein
GO:0008083 IEA growth factor activity
GO:0008201 IEA heparin binding
GO:0016525 IEA negative regulation of angiogenesis
GO:0016529 IDA sarcoplasmic reticulum
GO:0031012 IDA extracellular matrix
GO:0034103 IMP regulation of tissue remodeling
GO:0034976 IMP response to endoplasmic reticulum stress
GO:0048266 IMP behavioral response to pain
GO:0048771 IEA tissue remodeling
GO:0050731 IEA positive regulation of peptidyl-tyrosine phosphorylation
GO:0051451 IEA myoblast migration
GO:0051781 IEA positive regulation of cell division
GO:0070062 IEA extracellular vesicular exosome
GO:0071603 IEA endothelial cell-cell adhesion
GO:0090023 IEA positive regulation of neutrophil chemotaxis

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000020072 thbs4b thrombospondin 4b protein_coding Danio_rerio
ENSDARG00000052631 thbs4a thrombospondin 4a protein_coding Danio_rerio
ENSG00000113296 THBS4 thrombospondin 4 protein_coding Homo_sapiens

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