C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: thrombospondin 4
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000113296 THBS4 9606 + 5:79991311-80083287 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000350881 THBS4-001 80035348-80083287 protein_coding
  ENST00000504720 THBS4-004 80078835-80083287 processed_transcript
  ENST00000510218 THBS4-006 79991332-80055967 processed_transcript
  ENST00000511733 THBS4-005 80036023-80083282 protein_coding
  ENST00000511888 THBS4-003 80082004-80083188 processed_transcript
  ENST00000513310 THBS4-007 79991311-80055906 processed_transcript
  ENST00000515510 THBS4-002 80073272-80076879 processed_transcript

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENST00000350881ENST00000504720ENST00000511733ENST00000515510
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENST00000350881 7.649±0.00 7.344±0.00 N/A 8.293±0.00 20.261±10.93 16.320±13.76 15.458±11.43 0.231±0.00 1.105±0.00 1.005±0.22 14.582±2.64 5.904±4.73 0.188±0.07 9.532±6.48
ENST00000504720 N/A N/A N/A N/A N/A N/A N/A N/A N/A 1.232±0.00 N/A N/A 0.236±0.00 N/A
ENST00000511733 N/A N/A 0.016±0.00 1.984±0.00 4.263±0.00 0.809±0.00 N/A 0.064±0.00 N/A 0.236±0.00 N/A 0.825±0.00 N/A N/A
ENST00000515510 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A 0.197±0.00 N/A

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0005TF CIL_0005TF_0002 CGP 5:79976731-80083287
CIL_0005TG CIL_0005TG_0002 CGP 5:79991311-80256079

Gene Ontology
GO IDEvidence TypeGO Description
GO:0001938 IDA positive regulation of endothelial cell proliferation
GO:0005178 IDA integrin binding
GO:0005509 IEA:IDA calcium ion binding
GO:0005515 IPI:IEA protein binding
GO:0005576 TAS:IEA extracellular region
GO:0005604 IDA basement membrane
GO:0005615 IDA extracellular space
GO:0005783 ISS endoplasmic reticulum
GO:0006986 IEA response to unfolded protein
GO:0007155 IEA cell adhesion
GO:0008083 IEA growth factor activity
GO:0008201 IDA heparin binding
GO:0016525 IEP negative regulation of angiogenesis
GO:0016529 ISS sarcoplasmic reticulum
GO:0031012 ISS extracellular matrix
GO:0034103 ISS regulation of tissue remodeling
GO:0034976 ISS response to endoplasmic reticulum stress
GO:0048266 ISS behavioral response to pain
GO:0048771 IEA tissue remodeling
GO:0050731 IDA positive regulation of peptidyl-tyrosine phosphorylation
GO:0051451 IDA myoblast migration
GO:0051781 IEA positive regulation of cell division
GO:0070062 IDA extracellular vesicular exosome
GO:0071603 IDA endothelial cell-cell adhesion
GO:0090023 IDA positive regulation of neutrophil chemotaxis

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000020072 thbs4b thrombospondin 4b protein_coding Danio_rerio
ENSDARG00000052631 thbs4a thrombospondin 4a protein_coding Danio_rerio
ENSMUSG00000021702 Thbs4 thrombospondin 4 protein_coding Mus_musculus

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