C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: SH3-domain binding protein 5 (BTK-associated)
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSMUSG00000021892 Sh3bp5 10090 - 14:31359880-31436078 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENSMUST00000091903 Sh3bp5-001 31373785-31436065 protein_coding
  ENSMUST00000100730 Sh3bp5-003 31373785-31417677 protein_coding
  ENSMUST00000140002 Sh3bp5-002 31359880-31436078 nonsense_mediated_decay
  ENSMUST00000147586 Sh3bp5-004 31377595-31407385 processed_transcript

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENSMUST00000091903ENSMUST00000100730ENSMUST00000140002ENSMUST00000147586
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENSMUST00000091903 14.365±3.26 7.079±1.32 19.070±0.72 42.518±18.55 10.773±2.95 2.504±0.28 14.460±1.66 15.809±3.68 15.238±6.99 19.578±4.51 12.819±3.46 12.061±6.56 10.356±3.87 7.671±0.00
ENSMUST00000100730 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A 6.882±0.76
ENSMUST00000140002 N/A 11.651±3.24 N/A 16.248±0.00 8.112±2.98 3.552±0.65 N/A N/A 5.685±0.96 9.725±1.31 N/A 11.950±3.82 N/A 12.765±8.40
ENSMUST00000147586 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A 90.375±0.00

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0007WP CIL_0007WP_0002 VISTA 14:30932335-31535522
CIL_0002EF CIL_0002EF_0003 CGP 14:31336638-31436078
CIL_0005AH CIL_0005AH_0002 CGP 14:31359880-31495030

Gene Ontology
GO IDEvidence TypeGO Description
GO:0004860 ISO protein kinase inhibitor activity
GO:0005515 IEA protein binding
GO:0005737 IC cytoplasm
GO:0006469 IDA negative regulation of protein kinase activity
GO:0017124 TAS SH3 domain binding
GO:0035556 ISO intracellular signal transduction

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000013657 sh3bp5b SH3-domain binding protein 5b (BTK-associated) protein_coding Danio_rerio
ENSG00000131370 SH3BP5 SH3-domain binding protein 5 (BTK-associated) protein_coding Homo_sapiens

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