C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: SH3-domain binding protein 5 (BTK-associated)
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000131370 SH3BP5 9606 - 3:15254853-15341368 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000366391 SH3BP5-009 15258865-15276045 protein_coding
  ENST00000383791 SH3BP5-001 15254853-15332629 protein_coding
  ENST00000408919 SH3BP5-004 15255650-15341368 protein_coding
  ENST00000412806 SH3BP5-003 15255004-15332556 nonsense_mediated_decay
  ENST00000417936 SH3BP5-008 15262161-15275909 protein_coding
  ENST00000426925 SH3BP5-002 15255589-15333189 protein_coding
  ENST00000450625 SH3BP5-005 15262158-15332476 nonsense_mediated_decay
  ENST00000459627 SH3BP5-006 15304102-15332063 processed_transcript
  ENST00000465894 SH3BP5-007 15269843-15341237 processed_transcript

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENST00000383791ENST00000408919ENST00000412806
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENST00000383791 100.113±0.00 35.859±0.00 1.198±0.00 15.812±9.63 18.655±17.02 18.778±17.29 6.506±0.00 11.871±9.89 4.958±2.33 22.957±17.81 8.277±4.45 27.574±37.85 24.822±12.19 27.899±12.10
ENST00000408919 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A 3.589±0.00 16.687±0.00 15.816±0.00
ENST00000412806 39.627±0.00 17.746±0.00 N/A 9.824±0.00 6.713±5.42 7.407±5.79 0.468±0.00 N/A 2.294±0.00 14.216±10.43 N/A N/A N/A 20.821±0.00

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0002EF CIL_0002EF_0002 CGP 3:15206152-15341368
CIL_0005AH CIL_0005AH_0001 CGP 3:15254853-15440566

Gene Ontology
GO IDEvidence TypeGO Description
GO:0004860 IDA protein kinase inhibitor activity
GO:0005515 IPI protein binding
GO:0005737 TAS cytoplasm
GO:0006469 IEA negative regulation of protein kinase activity
GO:0007165 TAS signal transduction
GO:0017124 IEA SH3 domain binding
GO:0035556 IDA intracellular signal transduction

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000013657 sh3bp5b SH3-domain binding protein 5b (BTK-associated) protein_coding Danio_rerio
ENSMUSG00000021892 Sh3bp5 SH3-domain binding protein 5 (BTK-associated) protein_coding Mus_musculus

Loading