C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: integral membrane protein 2B
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSMUSG00000022108 Itm2b 10090 - 14:73362231-73385271 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENSMUST00000022704 Itm2b-201 73362231-73385271 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENSMUST00000022704
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENSMUST00000022704 821.381±163.74 874.709±134.16 613.570±27.48 107.035±54.15 821.421±121.63 682.875±144.44 265.606±70.24 923.044±368.39 493.644±329.37 937.257±106.89 69.895±18.21 679.713±325.54 136.760±74.61 179.044±85.87

Conserved Regions

Gene is not located within a conserved region.

Gene Ontology
GO IDEvidence TypeGO Description
GO:0001540 IEA beta-amyloid binding
GO:0005515 IPI protein binding
GO:0005524 IDA ATP binding
GO:0005615 ISS extracellular space
GO:0005768 IEA endosome
GO:0005794 IEA Golgi apparatus
GO:0005886 ISS plasma membrane
GO:0016020 IEA membrane
GO:0030660 ISS Golgi-associated vesicle membrane
GO:0031301 ISS integral component of organelle membrane
GO:0042985 ISS negative regulation of amyloid precursor protein biosynthetic process
GO:0043231 IEA intracellular membrane-bounded organelle
GO:0070062 IEA extracellular vesicular exosome
GO:0097192 IDA extrinsic apoptotic signaling pathway in absence of ligand

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000007098 itm2ba integral membrane protein 2Ba protein_coding Danio_rerio
ENSDARG00000041505 itm2bb integral membrane protein 2Bb protein_coding Danio_rerio
ENSG00000136156 ITM2B integral membrane protein 2B protein_coding Homo_sapiens

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