C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: endothelin receptor type B
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSMUSG00000022122 Ednrb 10090 - 14:103814625-103844173 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENSMUST00000022718 Ednrb-201 103814625-103844173 protein_coding
  ENSMUST00000172237 Ednrb-202 103814626-103843696 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENSMUST00000022718ENSMUST00000172237
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENSMUST00000022718 2.474±0.23 1.025±0.33 1.866±0.82 4.124±4.11 1.878±1.91 0.662±0.24 0.993±0.04 1.597±0.61 0.661±0.38 8.295±1.28 0.710±0.39 1.921±1.78 5.176±3.12 0.095±0.08
ENSMUST00000172237 4.414±0.79 2.956±0.47 3.063±0.03 3.274±2.11 4.756±0.87 1.719±0.27 2.332±0.47 2.710±1.16 1.561±0.39 8.078±5.71 0.733±0.30 2.516±1.08 2.851±2.07 0.208±0.05

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_00086M CIL_00086M_0002 VISTA 14:103463360-104064966
CIL_00004C CIL_00004C_0002 CGP 14:103650228-103844173
CIL_0000U0 CIL_0000U0_0002 CGP 14:103814625-104467999

Gene Ontology
GO IDEvidence TypeGO Description
GO:0000122 IDA negative regulation of transcription from RNA polymerase II promoter
GO:0001755 IMP neural crest cell migration
GO:0001934 IEA positive regulation of protein phosphorylation
GO:0004962 IMP endothelin receptor activity
GO:0005515 IPI protein binding
GO:0005886 IEA plasma membrane
GO:0006885 IMP regulation of pH
GO:0007186 IDA G-protein coupled receptor signaling pathway
GO:0007200 IEA phospholipase C-activating G-protein coupled receptor signaling pathway
GO:0007204 IEA positive regulation of cytosolic calcium ion concentration
GO:0007422 IMP peripheral nervous system development
GO:0007497 IMP posterior midgut development
GO:0007568 IEA aging
GO:0008217 IMP regulation of blood pressure
GO:0008284 IEA positive regulation of cell proliferation
GO:0014043 IDA negative regulation of neuron maturation
GO:0014070 IEA response to organic cyclic compound
GO:0014826 IEA vein smooth muscle contraction
GO:0016020 IEA membrane
GO:0016021 IEA integral component of membrane
GO:0017046 IEA peptide hormone binding
GO:0019233 IEA sensory perception of pain
GO:0019934 IEA cGMP-mediated signaling
GO:0030318 IMP melanocyte differentiation
GO:0031620 IEA regulation of fever generation
GO:0031702 IEA type 1 angiotensin receptor binding
GO:0031965 IEA nuclear membrane
GO:0032269 IEA negative regulation of cellular protein metabolic process
GO:0032496 IEA response to lipopolysaccharide
GO:0035645 IDA enteric smooth muscle cell differentiation
GO:0035810 IEA positive regulation of urine volume
GO:0035815 IEA positive regulation of renal sodium excretion
GO:0042045 IEA epithelial fluid transport
GO:0042310 IEA vasoconstriction
GO:0042311 IEA vasodilation
GO:0043066 IEA negative regulation of apoptotic process
GO:0043473 IMP pigmentation
GO:0045121 IEA membrane raft
GO:0048066 IMP developmental pigmentation
GO:0048246 IEA macrophage chemotaxis
GO:0048265 IEA response to pain
GO:0048484 IDA enteric nervous system development
GO:0050678 IEA regulation of epithelial cell proliferation
GO:0051930 IEA regulation of sensory perception of pain
GO:0060406 IEA positive regulation of penile erection
GO:0071222 IEA cellular response to lipopolysaccharide
GO:0086100 IEA endothelin receptor signaling pathway

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000089334 ednrb1a endothelin receptor B1a protein_coding Danio_rerio
ENSG00000136160 EDNRB endothelin receptor type B protein_coding Homo_sapiens

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