C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: immunoresponsive gene 1
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSMUSG00000022126 Irg1 10090 + 14:103046977-103056573 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENSMUST00000022722 Irg1-001 103046977-103056573 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungOvaryPlacentaENSMUST00000022722
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Ovary Placenta
ENSMUST00000022722 2.863±2.81 0.045±0.01 0.048±0.02 0.007±0.00 0.074±0.05 0.209±0.08 0.028±0.01 0.021±0.01 0.060±0.01 0.058±0.04 0.326±0.25 0.070±0.06

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_000049 CIL_000049_0002 CGP 14:102976581-103056573
CIL_00004A CIL_00004A_0002 CGP 14:103046977-103077579

Gene Ontology
GO IDEvidence TypeGO Description
GO:0002760 IDA positive regulation of antimicrobial humoral response
GO:0005739 IDA mitochondrion
GO:0006952 IDA defense response
GO:0006954 IEA inflammatory response
GO:0007566 IMP embryo implantation
GO:0008152 IDA metabolic process
GO:0019543 IEA propionate catabolic process
GO:0032088 IMP negative regulation of NF-kappaB transcription factor activity
GO:0032480 IMP negative regulation of type I interferon production
GO:0032496 IDA response to lipopolysaccharide
GO:0034136 IMP negative regulation of toll-like receptor 2 signaling pathway
GO:0034144 IDA negative regulation of toll-like receptor 4 signaling pathway
GO:0035458 IDA cellular response to interferon-beta
GO:0045824 IDA negative regulation of innate immune response
GO:0047547 IEA 2-methylcitrate dehydratase activity
GO:0047613 IDA aconitate decarboxylase activity
GO:0050728 IDA negative regulation of inflammatory response
GO:0071219 IDA cellular response to molecule of bacterial origin
GO:0071222 IDA cellular response to lipopolysaccharide
GO:0071346 IDA cellular response to interferon-gamma
GO:0071347 IDA cellular response to interleukin-1
GO:0071356 IDA cellular response to tumor necrosis factor
GO:0071393 IDA cellular response to progesterone stimulus
GO:0072573 IDA tolerance induction to lipopolysaccharide
GO:2000379 IDA positive regulation of reactive oxygen species metabolic process

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000069844 irg1 immunoresponsive gene 1 protein_coding Danio_rerio
ENSG00000102794 IRG1 immunoresponsive 1 homolog (mouse) protein_coding Homo_sapiens

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