C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: natriuretic peptide receptor 3
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSMUSG00000022206 Npr3 10090 - 15:11839896-11905674 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENSMUST00000066529 Npr3-201 11839896-11905674 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENSMUST00000066529
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENSMUST00000066529 45.501±32.55 2.535±2.77 0.758±0.08 1.031±0.26 11.811±6.17 0.757±0.13 2.435±0.38 2.647±0.56 0.770±0.41 9.636±5.10 0.480±0.44 4.784±2.54 1.112±0.90 0.413±0.17

Conserved Regions

Gene is not located within a conserved region.

Gene Ontology
GO IDEvidence TypeGO Description
GO:0001501 IDA skeletal system development
GO:0002158 IMP osteoclast proliferation
GO:0007193 IEA adenylate cyclase-inhibiting G-protein coupled receptor signaling pathway
GO:0007194 IEA negative regulation of adenylate cyclase activity
GO:0007200 IEA phospholipase C-activating G-protein coupled receptor signaling pathway
GO:0008217 IMP regulation of blood pressure
GO:0008528 IEA G-protein coupled peptide receptor activity
GO:0016020 IEA membrane
GO:0016021 IEA integral component of membrane
GO:0016941 ISS natriuretic peptide receptor activity
GO:0017046 IEA peptide hormone binding
GO:0030157 IEA pancreatic juice secretion
GO:0033688 IMP regulation of osteoblast proliferation
GO:0035810 IMP positive regulation of urine volume
GO:0042562 IEA hormone binding
GO:0042803 IEA protein homodimerization activity
GO:0048015 IEA phosphatidylinositol-mediated signaling
GO:0048662 IEA negative regulation of smooth muscle cell proliferation
GO:0051000 IEA positive regulation of nitric-oxide synthase activity
GO:0070062 IEA extracellular vesicular exosome

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000035253 npr3 natriuretic peptide receptor 3 protein_coding Danio_rerio
ENSG00000113389 NPR3 natriuretic peptide receptor 3 protein_coding Homo_sapiens

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