C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: natriuretic peptide receptor 3
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000113389 NPR3 9606 + 5:32689070-32791724 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000265074 NPR3-001 32711434-32791720 protein_coding
  ENST00000326958 NPR3-201 32710637-32791724 protein_coding
  ENST00000415167 NPR3-006 32711723-32786421 protein_coding
  ENST00000434067 NPR3-002 32709407-32786826 protein_coding
  ENST00000506712 NPR3-003 32710654-32783607 retained_intron
  ENST00000507141 NPR3-005 32712331-32716828 protein_coding
  ENST00000509104 NPR3-004 32689070-32783028 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENST00000265074ENST00000326958ENST00000415167ENST00000506712
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENST00000265074 N/A 0.246±0.00 N/A 0.136±0.11 10.970±0.00 0.652±0.00 0.701±0.09 2.527±0.00 0.298±0.23 2.718±1.61 N/A 0.786±0.75 0.662±0.31 N/A
ENST00000326958 0.686±0.00 0.270±0.00 2.656±0.00 0.154±0.12 6.946±5.01 1.163±0.55 2.994±0.52 7.922±0.00 0.116±0.05 4.234±0.73 0.148±0.00 0.320±0.00 0.410±0.00 0.219±0.00
ENST00000415167 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A 1.687±0.00 N/A 0.323±0.00
ENST00000506712 N/A N/A N/A N/A N/A 1.009±0.00 N/A N/A N/A N/A N/A N/A N/A N/A

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_000211 CIL_000211_0002 CGP 5:32531633-32791724

Gene Ontology
GO IDEvidence TypeGO Description
GO:0001501 ISS skeletal system development
GO:0002158 ISS osteoclast proliferation
GO:0005887 IC integral component of plasma membrane
GO:0007193 IEA adenylate cyclase-inhibiting G-protein coupled receptor signaling pathway
GO:0007194 IEA negative regulation of adenylate cyclase activity
GO:0007200 IEA phospholipase C-activating G-protein coupled receptor signaling pathway
GO:0008217 ISS regulation of blood pressure
GO:0008528 ISS G-protein coupled peptide receptor activity
GO:0016020 IEA membrane
GO:0016021 IEA integral component of membrane
GO:0016941 IDA natriuretic peptide receptor activity
GO:0017046 ISS peptide hormone binding
GO:0030157 IEA pancreatic juice secretion
GO:0033688 ISS regulation of osteoblast proliferation
GO:0035810 ISS positive regulation of urine volume
GO:0042562 IPI hormone binding
GO:0042803 IEA protein homodimerization activity
GO:0048015 IEA phosphatidylinositol-mediated signaling
GO:0048662 IEA negative regulation of smooth muscle cell proliferation
GO:0051000 ISS positive regulation of nitric-oxide synthase activity
GO:0070062 IDA extracellular vesicular exosome

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000035253 npr3 natriuretic peptide receptor 3 protein_coding Danio_rerio
ENSMUSG00000022206 Npr3 natriuretic peptide receptor 3 protein_coding Mus_musculus

Loading