C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: diacylglycerol O-acyltransferase 1
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSMUSG00000022555 Dgat1 10090 - 15:76502015-76511951 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENSMUST00000023214 Dgat1-001 76502015-76511951 protein_coding
  ENSMUST00000159776 Dgat1-004 76503952-76504663 retained_intron
  ENSMUST00000159908 Dgat1-007 76502068-76503314 retained_intron
  ENSMUST00000160293 Dgat1-008 76503276-76506605 protein_coding
  ENSMUST00000160294 Dgat1-002 76502017-76503180 retained_intron
  ENSMUST00000161499 Dgat1-003 76503902-76505195 retained_intron
  ENSMUST00000162354 Dgat1-006 76502524-76503945 nonsense_mediated_decay
  ENSMUST00000162813 Dgat1-005 76503591-76504322 retained_intron

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENSMUST00000023214ENSMUST00000159908ENSMUST00000160293ENSMUST00000160294ENSMUST00000162813
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENSMUST00000023214 135.578±39.95 53.742±20.11 12.005±2.33 12.243±7.62 111.149±19.10 23.880±4.42 13.553±1.31 24.634±4.84 11.204±3.28 19.130±4.33 3.357±0.73 23.370±7.48 12.463±5.95 45.482±22.28
ENSMUST00000159908 N/A 40.519±1.57 N/A N/A 72.881±1.95 23.849±5.99 8.148±0.00 N/A 13.634±3.63 N/A 3.077±0.00 28.532±6.16 9.934±0.00 N/A
ENSMUST00000160293 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A 5.370±0.00
ENSMUST00000160294 N/A N/A 6.061±0.03 13.959±2.24 44.871±0.00 17.917±3.76 7.847±2.34 12.965±1.91 5.492±1.70 11.481±2.20 N/A 20.061±1.54 5.042±0.00 N/A
ENSMUST00000162813 N/A N/A N/A 22.265±0.00 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0007SS CIL_0007SS_0002 VISTA 15:76102685-76704351
CIL_00026U CIL_00026U_0002 CGP 15:76477445-76511951
CIL_00026R CIL_00026R_0002 CGP 15:76502015-76522129

Gene Ontology
GO IDEvidence TypeGO Description
GO:0003846 IDA 2-acylglycerol O-acyltransferase activity
GO:0004144 IDA diacylglycerol O-acyltransferase activity
GO:0005515 IEA protein binding
GO:0005783 IEA endoplasmic reticulum
GO:0016020 IDA membrane
GO:0016021 IDA integral component of membrane
GO:0019432 IDA triglyceride biosynthetic process
GO:0019915 IGI lipid storage
GO:0034379 IEA very-low-density lipoprotein particle assembly
GO:0035336 IDA long-chain fatty-acyl-CoA metabolic process
GO:0042572 IEA retinol metabolic process
GO:0043231 IMP intracellular membrane-bounded organelle
GO:0046339 IDA diacylglycerol metabolic process
GO:0050252 IEA retinol O-fatty-acyltransferase activity
GO:0055089 IGI fatty acid homeostasis

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000031465 dgat1a diacylglycerol O-acyltransferase homolog 1a (mouse) protein_coding Danio_rerio
ENSDARG00000054914 dgat1b diacylglycerol O-acyltransferase homolog 1b (mouse) protein_coding Danio_rerio
ENSG00000185000 DGAT1 diacylglycerol O-acyltransferase 1 protein_coding Homo_sapiens

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