C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: heat shock factor 1
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSMUSG00000022556 Hsf1 10090 + 15:76477445-76500972 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENSMUST00000072838 Hsf1-201 76477445-76500972 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENSMUST00000072838
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENSMUST00000072838 22.499±6.84 19.240±6.34 27.302±0.76 21.872±12.25 21.338±6.37 17.775±2.42 14.057±1.97 15.001±1.73 9.537±4.75 27.160±5.18 9.799±2.99 24.281±9.86 15.290±4.35 15.637±7.05

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0007SS CIL_0007SS_0002 VISTA 15:76102685-76704351
CIL_00064A CIL_00064A_0003 CGP 15:76457438-76500972
CIL_00026U CIL_00026U_0002 CGP 15:76477445-76511951

Gene Ontology
GO IDEvidence TypeGO Description
GO:0000122 IEA negative regulation of transcription from RNA polymerase II promoter
GO:0000978 IEA RNA polymerase II core promoter proximal region sequence-specific DNA binding
GO:0001078 IEA RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in negative regulation of transcription
GO:0001162 IEA RNA polymerase II intronic transcription regulatory region sequence-specific DNA binding
GO:0001701 IMP in utero embryonic development
GO:0001892 IMP embryonic placenta development
GO:0003677 IDA DNA binding
GO:0003682 IDA chromatin binding
GO:0005515 IEA protein binding
GO:0005634 IDA nucleus
GO:0005737 IDA cytoplasm
GO:0006351 IEA transcription, DNA-templated
GO:0006468 IDA protein phosphorylation
GO:0006952 IEA defense response
GO:0007143 IMP female meiotic division
GO:0007283 IGI spermatogenesis
GO:0008285 IGI negative regulation of cell proliferation
GO:0009408 IMP response to heat
GO:0032496 IMP response to lipopolysaccharide
GO:0032720 IMP negative regulation of tumor necrosis factor production
GO:0034605 ISS cellular response to heat
GO:0040018 IMP positive regulation of multicellular organism growth
GO:0043234 IPI protein complex
GO:0043565 IDA sequence-specific DNA binding
GO:0045120 IDA pronucleus
GO:0045944 IEA positive regulation of transcription from RNA polymerase II promoter
GO:0060136 IMP embryonic process involved in female pregnancy
GO:0090231 IMP regulation of spindle checkpoint

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000008818 hsf1 heat shock transcription factor 1 protein_coding Danio_rerio
ENSG00000185122 HSF1 heat shock transcription factor 1 protein_coding Homo_sapiens

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