C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: heat shock transcription factor 1
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000185122 HSF1 9606 + 8:144291591-144314722 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000400780 HSF1-006 144291591-144314668 protein_coding
  ENST00000527328 HSF1-005 144310399-144314716 retained_intron
  ENST00000528199 HSF1-014 144309196-144311382 retained_intron
  ENST00000528838 HSF1-001 144291598-144314722 protein_coding
  ENST00000528842 HSF1-010 144313041-144314204 retained_intron
  ENST00000528988 HSF1-003 144291605-144309594 nonsense_mediated_decay
  ENST00000529630 HSF1-009 144309269-144310094 retained_intron
  ENST00000530661 HSF1-012 144311766-144314176 nonsense_mediated_decay
  ENST00000531447 HSF1-013 144311054-144311610 retained_intron
  ENST00000532338 HSF1-002 144309034-144314719 retained_intron
  ENST00000533130 HSF1-007 144311175-144311887 retained_intron
  ENST00000533240 HSF1-004 144292580-144311367 protein_coding
  ENST00000534314 HSF1-008 144309458-144312091 nonsense_mediated_decay
  ENST00000614796 HSF1-011 144312613-144314720 retained_intron

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENST00000400780ENST00000528838ENST00000528988ENST00000531447ENST00000532338
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENST00000400780 18.101±0.00 15.116±0.00 1.464±0.00 N/A N/A N/A N/A 1.851±0.00 N/A 17.907±0.00 N/A 15.881±0.00 6.073±0.00 36.740±3.28
ENST00000528838 27.458±0.00 19.542±0.00 N/A 7.372±4.65 28.589±0.00 56.514±0.00 33.545±32.08 14.247±11.64 8.284±5.07 23.906±22.70 71.235±63.42 39.313±17.67 41.267±17.46 50.450±10.57
ENST00000528988 N/A N/A 3.475±0.00 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A
ENST00000531447 N/A N/A 6.341±0.00 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A
ENST00000532338 N/A N/A N/A N/A 0.525±0.00 N/A N/A N/A N/A N/A N/A N/A N/A N/A

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0007SS CIL_0007SS_0001 VISTA 8:143880613-144482307
CIL_00064A CIL_00064A_0002 CGP 8:144266560-144314722
CIL_00026U CIL_00026U_0001 CGP 8:144291591-144326910

Gene Ontology
GO IDEvidence TypeGO Description
GO:0000122 IDA negative regulation of transcription from RNA polymerase II promoter
GO:0000978 IDA RNA polymerase II core promoter proximal region sequence-specific DNA binding
GO:0001078 IDA RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in negative regulation of transcription
GO:0001162 IDA RNA polymerase II intronic transcription regulatory region sequence-specific DNA binding
GO:0001701 IEA in utero embryonic development
GO:0001892 IEA embryonic placenta development
GO:0003677 IEA DNA binding
GO:0003682 IEA chromatin binding
GO:0003700 IEA sequence-specific DNA binding transcription factor activity
GO:0005515 IPI protein binding
GO:0005634 IEA nucleus
GO:0005737 IDA cytoplasm
GO:0006351 IEA transcription, DNA-templated
GO:0006355 IEA regulation of transcription, DNA-templated
GO:0006468 IEA protein phosphorylation
GO:0006952 IEA defense response
GO:0007143 IEA female meiotic division
GO:0007283 IEA spermatogenesis
GO:0008285 IEA negative regulation of cell proliferation
GO:0009408 IEA response to heat
GO:0032496 IEA response to lipopolysaccharide
GO:0032720 IEA negative regulation of tumor necrosis factor production
GO:0034605 IDA cellular response to heat
GO:0040018 IEA positive regulation of multicellular organism growth
GO:0043234 IEA protein complex
GO:0043565 IEA sequence-specific DNA binding
GO:0045120 IEA pronucleus
GO:0045944 IDA positive regulation of transcription from RNA polymerase II promoter
GO:0060136 IEA embryonic process involved in female pregnancy
GO:0090231 IEA regulation of spindle checkpoint

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000008818 hsf1 heat shock transcription factor 1 protein_coding Danio_rerio
ENSMUSG00000022556 Hsf1 heat shock factor 1 protein_coding Mus_musculus

Loading