C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: dopamine receptor D3
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSMUSG00000022705 Drd3 10090 + 16:43762221-43822932 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENSMUST00000023390 Drd3-201 43762221-43822932 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBrainColonHeartKidneyLiverLungOvaryPlacentaTestisENSMUST00000023390
Transcript ID Adipose Adrenal Brain Colon Heart Kidney Liver Lung Ovary Placenta Testis
ENSMUST00000023390 0.056±0.04 0.079±0.03 0.096±0.05 0.226±0.10 0.017±0.00 0.055±0.05 0.021±0.01 0.037±0.02 0.084±0.05 0.075±0.09 0.019±0.00

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0003CD CIL_0003CD_0002 CGP 16:43762221-43926809

Gene Ontology
GO IDEvidence TypeGO Description
GO:0000122 IEA negative regulation of transcription from RNA polymerase II promoter
GO:0001591 IDA dopamine neurotransmitter receptor activity, coupled via Gi/Go
GO:0001963 IEA synaptic transmission, dopaminergic
GO:0001975 IGI response to amphetamine
GO:0002016 IGI regulation of blood volume by renin-angiotensin
GO:0002031 IEA G-protein coupled receptor internalization
GO:0004952 IEA dopamine neurotransmitter receptor activity
GO:0005515 IPI protein binding
GO:0005886 IDA plasma membrane
GO:0005887 IEA integral component of plasma membrane
GO:0006874 IEA cellular calcium ion homeostasis
GO:0007191 IDA adenylate cyclase-activating dopamine receptor signaling pathway
GO:0007194 IEA negative regulation of adenylate cyclase activity
GO:0007195 IEA adenylate cyclase-inhibiting dopamine receptor signaling pathway
GO:0007212 IEA dopamine receptor signaling pathway
GO:0007626 IGI locomotory behavior
GO:0008144 IEA drug binding
GO:0008284 IEA positive regulation of cell proliferation
GO:0008542 IMP visual learning
GO:0014059 IMP regulation of dopamine secretion
GO:0016020 IDA membrane
GO:0019216 IMP regulation of lipid metabolic process
GO:0019904 IEA protein domain specific binding
GO:0030139 IEA endocytic vesicle
GO:0030814 IEA regulation of cAMP metabolic process
GO:0031748 IEA D1 dopamine receptor binding
GO:0032416 IEA negative regulation of sodium:proton antiporter activity
GO:0032467 IEA positive regulation of cytokinesis
GO:0032922 IMP circadian regulation of gene expression
GO:0034776 IEA response to histamine
GO:0035240 IEA dopamine binding
GO:0035483 IEA gastric emptying
GO:0035815 IEA positive regulation of renal sodium excretion
GO:0040012 IEA regulation of locomotion
GO:0040014 IMP regulation of multicellular organism growth
GO:0042220 IMP response to cocaine
GO:0042493 IEA response to drug
GO:0042995 IEA cell projection
GO:0043278 IMP response to morphine
GO:0045177 IEA apical part of cell
GO:0045187 IEA regulation of circadian sleep/wake cycle, sleep
GO:0045471 IMP response to ethanol
GO:0045776 IMP negative regulation of blood pressure
GO:0045840 IEA positive regulation of mitosis
GO:0045944 IEA positive regulation of transcription from RNA polymerase II promoter
GO:0046717 IEA acid secretion
GO:0048148 IMP behavioral response to cocaine
GO:0048715 IDA negative regulation of oligodendrocyte differentiation
GO:0050482 IEA arachidonic acid secretion
GO:0050709 IEA negative regulation of protein secretion
GO:0050883 IMP musculoskeletal movement, spinal reflex action
GO:0051898 IMP negative regulation of protein kinase B signaling
GO:0060134 IEA prepulse inhibition
GO:0060160 IGI negative regulation of dopamine receptor signaling pathway
GO:0060161 IMP positive regulation of dopamine receptor signaling pathway
GO:0090325 IEA regulation of locomotion involved in locomotory behavior

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000032131 drd3 dopamine receptor D3 protein_coding Danio_rerio
ENSG00000151577 DRD3 dopamine receptor D3 protein_coding Homo_sapiens

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